PDB entry 3cjc

View 3cjc on RCSB PDB site
Description: Actin dimer cross-linked by V. cholerae MARTX toxin and complexed with DNase I and Gelsolin-segment 1
Class: Structural protein/Hydrolase
Keywords: cross-linked dimer, ATP-binding, Cytoskeleton, Methylation, Muscle protein, Nucleotide-binding, Phosphoprotein, Structural protein, Actin-binding, Apoptosis, Endonuclease, Glycoprotein, Hydrolase, Nuclease, Nucleus, Secreted, Actin capping, Alternative initiation, Amyloid, Disease mutation, Structural protein-Hydrolase COMPLEX
Deposited on 2008-03-12, released 2008-03-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 3.9 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Deoxyribonuclease-1
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3cjcd1
  • Chain 'G':
    Compound: gelsolin
    Species: Homo sapiens [TaxId:9606]
    Gene: GSN
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3cjcg1
  • Heterogens: CA, SO4, ATP, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3cjcD (D:)
lkiaafnirtfgetkmsnatlasyivrivrrydivliqevrdshlvavgklldylnqddp
ntyhyvvseplgrnsykerylflfrpnkvsvldtyqyddgcescgndsfsrepavvkfss
hstkvkefaivalhsapsdavaeinslydvyldvqqkwhlndvmlmgdfnadcsyvtssq
wssirlrtsstfqwlipdsadttatstncaydrivvagsllqssvvpgsaapfdfqaayg
lsnemalaisdhypvevtlt

    Sequence, based on observed residues (ATOM records): (download) 
    >3cjcD (D:)
lkiaafnirtfgetkmsnatlasyivrivrrydivliqevrdshlvavgklldylnqddp
ntyhyvvseplgrnsykerylflfrpnkvsvldtyqyddgccgndsfsrepavvkfsshs
tkvkefaivalhsapsdavaeinslydvyldvqqkwhlndvmlmgdfnadcsyvtssqws
sirlrtsstfqwlipdsadttatstncaydrivvagsllqssvvpgsaapfdfqaaygls
nemalaisdhypvevtlt

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3cjcG (G:)
mvvehpeflkagkepglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqyd
lhywlgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkgg
vasgf