PDB entry 3chs

View 3chs on RCSB PDB site
Description: Crystal structure of leukotriene A4 hydrolase in complex with (2S)-2-amino-5-[[4-[(2S)-2-hydroxy-2-phenyl-ethoxy]phenyl]amino]-5-oxo-pentanoic acid
Class: hydrolase
Keywords: EPOXIDE HYDROLASE, ALPHA-BETA PROTEIN, LEUKOTRIENE BIOSYNTHESIS, METALLOPROTEASE, Inhibitor complex, Alternative splicing, Cytoplasm, Metal-binding, Multifunctional enzyme, Zinc, HYDROLASE
Deposited on 2008-03-10, released 2008-04-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Leukotriene A-4 hydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: LTA4H, LTA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3chsa1, d3chsa2, d3chsa3
  • Heterogens: ZN, YB, IMD, 4BU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3chsA (A:)
peivdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdlt
iekvvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwltp
eqtsgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetpd
pedpsrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetesm
lkiaedlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnviaheishs
wtgnlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfgeth
pftklvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksit
tddwkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitake
ddlnsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwlr
lciqskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvta
mlvgkdlkvd