PDB entry 3cft
View 3cft on RCSB PDB site
Description: Crystal structure of human transthyretin in complex with 1-amino-5-naphthalene sulfonate
Class: transport protein
Keywords: human wild-type transthyretin, thyroxin, amyloid, familial amyloid polyneurophaty, Disease mutation, Glycoprotein, Hormone, Polymorphism, Polyneuropathy, Retinol-binding, Secreted, Thyroid hormone, Transport, Vitamin A, TRANSPORT PROTEIN
Deposited on
2008-03-04, released
2009-03-03
The last revision prior to the SCOPe 2.06 freeze date was dated
2010-02-16, with a file datestamp of
2010-02-12.
Experiment type: XRAY
Resolution: 1.87 Å
R-factor: 0.194
AEROSPACI score: 0.48
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3cfta_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3cftb_ - Heterogens: 5NS, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3cftA (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnpke
Sequence, based on observed residues (ATOM records): (download)
>3cftA (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3cftB (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnpke
Sequence, based on observed residues (ATOM records): (download)
>3cftB (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn