PDB entry 3cf6
View 3cf6 on RCSB PDB site
Description: Structure of Epac2 in complex with cyclic-AMP and Rap
Class: signaling protein/GTP-binding protein
Keywords: epac, rapgef4, rap, rap1b, camp, sp-camps, gef, gunanine nucleotide exchange factor, g-protein, GTP-binding, nucleotide-binding, signaling protein regulator-GTP-binding protein complex, signaling protein-GTP-binding protein complex
Deposited on
2008-03-02, released
2008-07-29
The last revision prior to the SCOPe 2.07 freeze date was dated
2014-02-05, with a file datestamp of
2014-01-31.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.244
AEROSPACI score: 0.27
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'E':
Compound: Rap guanine nucleotide exchange factor (GEF) 4
Species: Mus musculus [TaxId:10090]
Gene: Rapgef4
Database cross-references and differences (RAF-indexed):
- Chain 'R':
Compound: Ras-related protein Rap-1b
Species: Homo sapiens [TaxId:9606]
Gene: RAP1B
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d3cf6r_ - Heterogens: SO4, SP1, HOH
PDB Chain Sequences:
- Chain 'E':
No sequence available.
- Chain 'R':
Sequence, based on SEQRES records: (download)
>3cf6R (R:)
mreyklvvlgsggvgksaltvqfvqgifvekydptiedsyrkqvevdaqqcmleildtag
teqftamrdlymkngqgfalvysitaqstfndlqdlreqilrvkdtddvpmilvgnkcdl
edervvgkeqgqnlarqwnncaflessakskinvneifydlvrqinr
Sequence, based on observed residues (ATOM records): (download)
>3cf6R (R:)
eyklvvlgsggvgksaltvqfvqgifvekydptiedsyrkqvqcmleildtagteqftam
rdlymkngqgfalvysitaqstfndlqdlreqilrvkdtddvpmilvgnkcdledervvg
keqgqnlaflessakskinvneifydlvrq