PDB entry 3cdg

View 3cdg on RCSB PDB site
Description: Human CD94/NKG2A in complex with HLA-E
Class: immune system
Keywords: NK cell receptor, immunity, C-type lectin, MHC, Glycoprotein, Immune response, Membrane, MHC I, Polymorphism, Transmembrane, Disease mutation, Glycation, Immunoglobulin domain, Pyrrolidone carboxylic acid, Secreted, Alternative splicing, Signal-anchor, IMMUNE SYSTEM
Deposited on 2008-02-26, released 2008-04-22
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-05-19, with a file datestamp of 2009-05-15.
Experiment type: XRAY
Resolution: 3.4 Å
R-factor: 0.25
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, alpha chain E
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-E, HLA-6.2, HLAE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3cdga1, d3cdga2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • expression tag (0)
    Domains in SCOPe 2.06: d3cdgb1, d3cdgb2
  • Chain 'C':
    Compound: HLA class I histocompatibility antigen, alpha chain E
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-E, HLA-6.2, HLAE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3cdgc1, d3cdgc2
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • expression tag (0)
    Domains in SCOPe 2.06: d3cdgd1, d3cdgd2
  • Chain 'E':
    Compound: Natural killer cells antigen CD94
    Species: Homo sapiens [TaxId:9606]
    Gene: KLRD1, CD94
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3cdge1
  • Chain 'F':
    Compound: NKG2-A/NKG2-B type II integral membrane protein
    Species: Homo sapiens [TaxId:9606]
    Gene: KLRC1, NKG2A
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: Natural killer cells antigen CD94
    Species: Homo sapiens [TaxId:9606]
    Gene: KLRD1, CD94
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3cdgj1
  • Chain 'K':
    Compound: NKG2-A/NKG2-B type II integral membrane protein
    Species: Homo sapiens [TaxId:9606]
    Gene: KLRC1, NKG2A
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: leader peptide of HLA class I histocompatibility antigen, alpha chain G
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'Q':
    Compound: leader peptide of HLA class I histocompatibility antigen, alpha chain G
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3cdgA (A:)
    shslkyfhtsvsrpgrgeprfisvgyvddtqfvrfdndaasprmvprapwmeqegseywd
    retrsardtaqifrvnlrtlrgyynqseagshtlqwmhgcelgpdrrflrgyeqfaydgk
    dyltlnedlrswtavdtaaqiseqksndaseaehqrayledtcvewlhkylekgketllh
    leppkthvthhpisdheatlrcwalgfypaeitltwqqdgeghtqdtelvetrpagdgtf
    qkwaavvvpsgeeqrytchvqheglpepvtlrw
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3cdgB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3cdgC (C:)
    shslkyfhtsvsrpgrgeprfisvgyvddtqfvrfdndaasprmvprapwmeqegseywd
    retrsardtaqifrvnlrtlrgyynqseagshtlqwmhgcelgpdrrflrgyeqfaydgk
    dyltlnedlrswtavdtaaqiseqksndaseaehqrayledtcvewlhkylekgketllh
    leppkthvthhpisdheatlrcwalgfypaeitltwqqdgeghtqdtelvetrpagdgtf
    qkwaavvvpsgeeqrytchvqheglpepvtlrw
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3cdgD (D:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3cdgE (E:)
    dccscqekwvgyrcncyfisseqktwnesrhlcasqkssllqlqntdeldfmsssqqfyw
    iglsyseehtawlwengsalsqylfpsfetfntknciaynpngnaldescedknryickq
    qli
    

  • Chain 'F':
    No sequence available.

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3cdgJ (J:)
    dccscqekwvgyrcncyfisseqktwnesrhlcasqkssllqlqntdeldfmsssqqfyw
    iglsyseehtawlwengsalsqylfpsfetfntknciaynpngnaldescedknryickq
    qli
    

  • Chain 'K':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    No sequence available.