PDB entry 3cbr
View 3cbr on RCSB PDB site
Description: Crystal structure of human Transthyretin (TTR) at pH3.5
Class: thyroxine binding protein
Keywords: TTR, AMYLOID, TRANSTHYRETIN, acidic pH, Disease mutation, Glycoprotein, Hormone, Polymorphism, Polyneuropathy, Retinol-binding, Secreted, Thyroid hormone, Vitamin A, TRANSPORT PROTEIN, THYROXINE BINDING PROTEIN
Deposited on
2008-02-22, released
2008-08-12
The last revision prior to the SCOPe 2.06 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.225
AEROSPACI score: 0.52
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: HOMO SAPIENS
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3cbra_ - Chain 'B':
Compound: Transthyretin
Species: HOMO SAPIENS
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3cbrb_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3cbrA (A:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>3cbrA (A:)
plmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiyk
veidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3cbrB (B:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>3cbrB (B:)
plmvkvldavrgspainvavhvfrkadtwepfasgktsesgelhgltteeefvegiykve
idtpfhehaevvftanrrytiaallspysysttavvt