PDB entry 3cbl

View 3cbl on RCSB PDB site
Description: Crystal structure of human feline sarcoma viral oncogene homologue (v-FES) in complex with staurosporine and a consensus peptide
Deposited on 2008-02-22, released 2008-03-04
The last revision was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.183
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Proto-oncogene tyrosine-protein kinase Fes/Fps
    Species: Homo sapiens [TaxId:9606]
    Gene: FES, FPS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07332 (2-End)
      • expression tag (0-1)
  • Chain 'B':
    Compound: synthetic peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3CBL (0-4)
  • Heterogens: STU, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3cblA (A:)
smipevqkplheqlwyhgaipraevaellvhsgdflvresqgkqeyvlsvlwdglprhfi
iqsldnlyrlegegfpsipllidhllstqqpltkksgvvlhravpkdkwvlnhedlvlge
qigrgnfgevfsgrlradntlvavkscretlppdlkakflqearilkqyshpnivrligv
ctqkqpiyivmelvqggdfltflrtegarlrvktllqmvgdaaagmeyleskccihrdla
arnclvteknvlkisdfgmsreeadgvyaasgglrqvpvkwtapealnygryssesdvws
fgillwetfslgaspypnlsnqqtrefvekggrlpcpelcpdavfrlmeqcwayepgqrp
sfstiyqelqsirkrhr

    Sequence, based on observed residues (ATOM records):
    >3cblA (A:)
smipevqkplheqlwyhgaipraevaellvhsgdflvresqqeyvlsvprhfiinlyrlf
psipllidhllstqqplvvlhravpkdkwvlnhedlvlgeqigrgnfgevfsgrlradnt
lvavkscretlppdlkakflqearilkqyshpnivrligvctqkqpiyivmelvqggdfl
tflrtegarlrvktllqmvgdaaagmeyleskccihrdlaarnclvteknvlkisdfgms
reeadgvyaasgglrqvpvkwtapealnygryssesdvwsfgillwetfslgaspypnls
nqqtrefvekggrlpcpelcpdavfrlmeqcwayepgqrpsfstiyqelqsirkrh

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >3cblB (B:)
iyesl