PDB entry 3cbj

View 3cbj on RCSB PDB site
Description: Chagasin-Cathepsin B complex
Class: hydrolase/hydrolase inhibitor
Keywords: chagasin, cathepsin B, occluding loop, Chagas disease, Glycoprotein, Hydrolase, Lysosome, Polymorphism, Protease, Thiol protease, Zymogen, Cytoplasmic vesicle, Protease inhibitor, Thiol protease inhibitor, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
Deposited on 2008-02-22, released 2008-05-27
The last revision prior to the SCOP 1.75 freeze date was dated 2008-06-10, with a file datestamp of 2008-06-06.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.165
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: cathepsin b
  Species: HOMO SAPIENS
  Gene: CTSB, CPSB
  Database cross-references and differences (RAF-indexed):
  • Uniprot P07858 (62-End)
    • engineered (34)
    • engineered (115)
    • engineered (120)
• Chain 'B':
  Compound: Chagasin
  Species: TRYPANOSOMA CRUZI
  Gene: cha
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q966X9 (Start-109)
  Domains in SCOP 1.75: d3cbjb1
• Heterogens: PO4, HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  Sequence, based on SEQRES records: (download)
  

  >3cbjB (B:)
  mshkvtkahngatltvavgelveiqlpsnpttgfawyfeggtkespnesmftvenkyfpp
  dskllgaggtehfhvtvkaagthavnltymrpwtgpshdserftvylkan
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >3cbjB (B:)
  shkvtkahngatltvavgelveiqlpsnpttgfawyfeggtkespnesmftvenkyfppd
  skllgaggtehfhvtvkaagthavnltymrpwtgpshdserftvylkan