PDB entry 3cbc

View 3cbc on RCSB PDB site
Description: Crystal structure of Siderocalin (NGAL, Lipocalin 2) Y106F complexed with Ferric Enterobactin
Class: antimicrobial protein
Keywords: Siderocalin, Ngal, 24p3, Enterobactin, Glycoprotein, Pyrrolidone carboxylic acid, Secreted, ANTIMICROBIAL PROTEIN
Deposited on 2008-02-21, released 2008-09-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2.17 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: LCN2, HNL, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188 (Start-197)
      • engineered (106)
      • engineered (125)
    Domains in SCOPe 2.08: d3cbca_
  • Chain 'B':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: LCN2, HNL, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188
      • engineered (106)
      • engineered (125)
    Domains in SCOPe 2.08: d3cbcb_
  • Chain 'C':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: LCN2, HNL, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188
      • engineered (106)
      • engineered (125)
    Domains in SCOPe 2.08: d3cbcc_
  • Heterogens: SO4, NA, DBS, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3cbcA (A:)
mplgllwlglallgalhaqaqdstsdlipapplskvplqqnfqdnqfqgkwyvvglagna
ilredkdpqkmyatiyelkedksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksy
pgltsflvrvvstnynqhamvffkkvsqnreyfkitlygrtkeltselkenfirfskslg
lpenhivfpvpidqcidg

    Sequence, based on observed residues (ATOM records): (download) 
    >3cbcA (A:)
stsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyelkedk
synvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsflvrvvstnynqhamvf
fkkvsqnreyfkitlygrtkeltselkenfirfskslglpenhivfpvpidqcidg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3cbcB (B:)
mplgllwlglallgalhaqaqdstsdlipapplskvplqqnfqdnqfqgkwyvvglagna
ilredkdpqkmyatiyelkedksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksy
pgltsflvrvvstnynqhamvffkkvsqnreyfkitlygrtkeltselkenfirfskslg
lpenhivfpvpidqcidg

    Sequence, based on observed residues (ATOM records): (download) 
    >3cbcB (B:)
tsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkpqkmyatiyelkedksy
nvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsflvrvvstnynqhamvffk
kvsqnreyfkitlygrtkeltselkenfirfskslglpenhivfpvpidqcid

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3cbcC (C:)
mplgllwlglallgalhaqaqdstsdlipapplskvplqqnfqdnqfqgkwyvvglagna
ilredkdpqkmyatiyelkedksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksy
pgltsflvrvvstnynqhamvffkkvsqnreyfkitlygrtkeltselkenfirfskslg
lpenhivfpvpidqcidg

    Sequence, based on observed residues (ATOM records): (download) 
    >3cbcC (C:)
stsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyelkedk
synvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsflvrvvstnynqhamvf
fkkvsqnreyfkitlygrtkeltselkenfirfskslglpenhivfpvpidqcid