PDB entry 3c9n

View 3c9n on RCSB PDB site
Description: Crystal Structure of a SARS Corona Virus Derived Peptide Bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501
Class: immune system
Keywords: MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I, MHC-I, HLA-B*1501, SARS, Glycoprotein, Host-virus interaction, Immune response, Membrane, MHC I, Polymorphism, Transmembrane, Ubl conjugation, Disease mutation, Glycation, Immunoglobulin domain, Pyrrolidone carboxylic acid, Secreted, IMMUNE SYSTEM
Deposited on 2008-02-18, released 2008-02-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.87 Å
R-factor: 0.19
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, B-15 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-B, HLAB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3c9na1, d3c9na2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3c9nb_
  • Chain 'C':
    Compound: Peptide antigen
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3C9N (0-8)
  • Heterogens: PG4, EPE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3c9nA (A:)
gshsmryfytamsrpgrgeprfiavgyvddtqfvrfdsdaasprmaprapwieqegpeyw
dretqisktntqtyreslrnlrgyynqseagshtlqrmygcdvgpdgrllrghdqsaydg
kdyialnedlsswtaadtaaqitqrkweaareaeqwrayleglcvewlrrylengketlq
radppkthvthhpisdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrt
fqkwaavvvpsgeeqrytchvqheglpkpltlrwep

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3c9nB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'C':
    No sequence available.