PDB entry 3c8x

View 3c8x on RCSB PDB site
Description: Crystal structure of the ligand binding domain of human Ephrin A2 (Epha2) receptor protein kinase
Class: transferase
Keywords: ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, RECEPTOR, TRANSFERASE, PHOSPHORYLATION, TRANSMEMBRANE, TYROSINE-PROTEIN KINASE, GLYCOPROTEIN, STRUCTURAL GENOMICS CONSORTIUM, SGC, Phosphoprotein
Deposited on 2008-02-14, released 2008-03-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ephrin type-A receptor 2
    Species: Homo sapiens [TaxId:9606]
    Gene: EPHA2, ECK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29317
      • see remark 999 (97-99)
      • see remark 999 (102)
    Domains in SCOPe 2.08: d3c8xa_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3c8xA (A:)
apehhhhhhdydipttenlyfqgamdaaqgkevvlldfaaaggelgwlthpygkgwdlmq
nimndmpiymysvcnvmsgdqdnwlrtnwvyrgeaerifielkftvrdcnsfpggassck
etfnlyyaesdldygtnfqkrlftkidtiapdeitvssdfearhvklnveersvgpltrk
gfylafqdigacvallsvrvyykkcp

    Sequence, based on observed residues (ATOM records): (download) 
    >3c8xA (A:)
kevvlldfaaalgwlthpygkgwdlmqnimndmpiymysvcnvmsgdqdnwlrtnwvyrg
eaerifielkftvrdcnsfpggasscketfnlyyaesdldygtnfqkrlftkidtiapdh
vklnveersvgpltrkgfylafqdigacvallsvrvyykk