PDB entry 3c7v

View 3c7v on RCSB PDB site
Description: Structural Insight into the Kinetics and Delta-Cp of interactions between TEM-1 Beta-Lactamase and BLIP
Class: hydrolase/hydrolase inhibitor
Keywords: enzyme-inhibitor complex, Antibiotic resistance, Hydrolase, Plasmid, Secreted, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
Deposited on 2008-02-08, released 2008-10-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-03-03, with a file datestamp of 2009-02-27.
Experiment type: XRAY
Resolution: 2.07 Å
R-factor: 0.216
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Escherichia coli [TaxId:562]
    Gene: bla, blaTEM-116
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3c7va_
  • Chain 'B':
    Compound: Beta-lactamase inhibitory protein
    Species: Streptomyces clavuligerus [TaxId:1901]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35804 (0-164)
      • engineered (50)
    Domains in SCOPe 2.08: d3c7vb_
  • Chain 'C':
    Compound: Beta-lactamase
    Species: Escherichia coli [TaxId:562]
    Gene: bla, blaTEM-116
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3c7vc_
  • Chain 'D':
    Compound: Beta-lactamase inhibitory protein
    Species: Streptomyces clavuligerus [TaxId:1901]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35804 (0-164)
      • engineered (50)
    Domains in SCOPe 2.08: d3c7vd_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3c7vA (A:)
    hpetlvkvkdaedqlgarvgyieldlnsgkilesfrpeerfpmmstfkvllcgavlsrid
    agqeqlgrrihysqndlveyspvtekhltdgmtvrelcsaaitmsdntaanlllttiggp
    keltaflhnmgdhvtrldrwepelneaipnderdttmpvamattlrklltgelltlasrq
    qlidwmeadkvagpllrsalpagwfiadksgagergsrgiiaalgpdgkpsrivviyttg
    sqatmdernrqiaeigaslikhw
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3c7vB (B:)
    agvmtgakftqiqfgmtrqqvldiagaencetggsfgdsihcrghaagdyaayatfgfts
    aaadakvdsksqekllapsaptltlakfnqvtvgmtraqvlatvgqgscttwseyypayp
    stagvtlslscfdvdgysstgfyrgsahlwftdgvlqgkrqwdlv
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3c7vC (C:)
    hpetlvkvkdaedqlgarvgyieldlnsgkilesfrpeerfpmmstfkvllcgavlsrid
    agqeqlgrrihysqndlveyspvtekhltdgmtvrelcsaaitmsdntaanlllttiggp
    keltaflhnmgdhvtrldrwepelneaipnderdttmpvamattlrklltgelltlasrq
    qlidwmeadkvagpllrsalpagwfiadksgagergsrgiiaalgpdgkpsrivviyttg
    sqatmdernrqiaeigaslikhw
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3c7vD (D:)
    agvmtgakftqiqfgmtrqqvldiagaencetggsfgdsihcrghaagdyaayatfgfts
    aaadakvdsksqekllapsaptltlakfnqvtvgmtraqvlatvgqgscttwseyypayp
    stagvtlslscfdvdgysstgfyrgsahlwftdgvlqgkrqwdlv