PDB entry 3c7q

View 3c7q on RCSB PDB site
Description: Structure of VEGFR2 kinase domain in complex with BIBF1120
Class: transferase
Keywords: ALPHA BETA, Angiogenesis, ATP-binding, Developmental protein, Differentiation, Glycoprotein, Host-virus interaction, Immunoglobulin domain, Kinase, Membrane, Nucleotide-binding, Phosphoprotein, Receptor, Transferase, Transmembrane, Tyrosine-protein kinase
Deposited on 2008-02-08, released 2008-12-23
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.221
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Vascular endothelial growth factor receptor 2
    Species: Homo sapiens [TaxId:9606]
    Gene: KDR, FLK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3c7qa_
  • Heterogens: SO4, XIN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3c7qA (A:)
gsmdpdelpldehcerlpydaskwefprdrlklgkplgrgafgqvieadafgidktatcr
tvavkmlkegathsehralmselkilihighhlnvvnllgactkpggplmvivefckfgn
lstylrskrnefvpykpedlykdfltlehlicysfqvakgmeflasrkcihrdlaarnil
lseknvvkicdfglardiykdpdyvrkgdarlplkwmapetifdrvytiqsdvwsfgvll
weifslgaspypgvkideefcrrlkegtrmrapdyttpemyqtmldcwhgepsqrptfse
lvehlgnllqanaqqd

    Sequence, based on observed residues (ATOM records): (download) 
    >3c7qA (A:)
rlpydaskwefprdrlklgkplgrgafgqvieadafgidktatcrtvavkmlkegathse
hralmselkilihighhlnvvnllgactkpggplmvivefckfgnlstylrskrnefvpy
kdfltlehlicysfqvakgmeflasrkcihrdlaarnillseknvvkicdfdiykdpdyv
rkgdarlplkwmapetifdrvytiqsdvwsfgvllweifslgaspypgvkideefcrrlk
egtrmrapdyttpemyqtmldcwhgepsqrptfselvehlgnllqanaqqd