PDB entry 3c72

View 3c72 on RCSB PDB site
Description: Engineered RabGGTase in complex with a peptidomimetic inhibitor
Class: transferase
Keywords: peptide inhibitor, Rab prenylation, Metal-binding, Prenyltransferase, Transferase, Phosphoprotein
Deposited on 2008-02-06, released 2008-07-22
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.192
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Geranylgeranyl transferase type-2 subunit alpha
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Rabggta, Ggta
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q08602 (Start-239)
      • linker (240-242)
    • Uniprot Q08602 (245-333)
  • Chain 'B':
    Compound: Geranylgeranyl transferase type-2 subunit beta
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Rabggtb, Ggtb
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3c72b_
  • Heterogens: ZN, CA, CX1, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3c72B (B:)
mgtqqkdvtiksdapdtlllekhadyiasygskkddyeycmseylrmsgvywgltvmdlm
gqlhrmnkeeilvfikscqhecggvsasighdphllytlsavqiltlydsihvinvdkvv
ayvqslqkedgsfagdiwgeidtrfsfcavatlallgkldainvekaiefvlscmnfdgg
fgcrpgseshagqiycctgflaitsqlhqvnsdllgwwlcerqlpsgglngrpeklpdvc
yswwvlaslkiigrlhwidreklrsfilacqdeetggfadrpgdmvdpfhtlfgiaglsl
lgeeqikpvspvfcmpeevlqrvnvqpelvs

    Sequence, based on observed residues (ATOM records): (download) 
    >3c72B (B:)
dvtiksdapdtlllekhadyiasygskddyeycmseylrmsgvywgltvmdlmgqlhrmn
keeilvfikscqhecggvsasighdphllytlsavqiltlydsihvinvdkvvayvqslq
kedgsfagdiwgeidtrfsfcavatlallgkldainvekaiefvlscmnfdggfgcrpgs
eshagqiycctgflaitsqlhqvnsdllgwwlcerqlpsgglngrpeklpdvcyswwvla
slkiigrlhwidreklrsfilacqdeetggfadrpgdmvdpfhtlfgiaglsllgeeqik
pvspvfcmpeevlqrvnvqpelvs