PDB entry 3c6l

View 3c6l on RCSB PDB site
Description: Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR 2W20
Class: sugar binding protein/immune system
Keywords: TCR-pMHC complex, Glycoprotein, Immune response, Membrane, MHC II, Transmembrane, SUGAR BINDING PROTEIN/IMMUNE SYSTEM COMPLEX
Deposited on 2008-02-04, released 2008-04-29
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.4 Å
R-factor: 0.268
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: TCR 2W20 alpha chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3C6L (0-184)
    Domains in SCOPe 2.04: d3c6la1, d3c6la2
  • Chain 'B':
    Compound: TCR 2W20 beta chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3C6L (0-235)
  • Chain 'C':
    Compound: H-2 class II histocompatibility antigen, A-B alpha chain
    Species: Mus musculus [TaxId:10090]
    Gene: H2-Aa
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3c6lc1, d3c6lc2
  • Chain 'D':
    Compound: 3K peptide, Linker,and H-2 class II histocompatibility antigen (A beta chain)
    Species: Mus musculus [TaxId:10090]
    Gene: H2-Ab1, H2-iabeta
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14483 (Start-216)
      • engineered (215)
    • PDB 3C6L (0-End)
    Domains in SCOPe 2.04: d3c6ld1, d3c6ld2
  • Chain 'E':
    Compound: TCR 2W20 alpha chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3C6L (0-End)
    Domains in SCOPe 2.04: d3c6le1, d3c6le2
  • Chain 'F':
    Compound: TCR 2W20 beta chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3C6L (0-235)
  • Chain 'G':
    Compound: H-2 class II histocompatibility antigen, A-B alpha chain
    Species: Mus musculus [TaxId:10090]
    Gene: H2-Aa
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3c6lg1, d3c6lg2
  • Chain 'H':
    Compound: 3K peptide, Linker,and H-2 class II histocompatibility antigen (A beta chain)
    Species: Mus musculus [TaxId:10090]
    Gene: H2-Ab1, H2-iabeta
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14483 (Start-216)
      • engineered (215)
    • PDB 3C6L (0-End)
    Domains in SCOPe 2.04: d3c6lh1, d3c6lh2
  • Heterogens: CA

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3c6lA (A:)
    qqvrqspqsltvwegetailncsyedstfdyfpwyhqfpgespalliairpvsnkkedgr
    ftiffnkrekkfslhiadsqpgdsatyfcaasdnriffgdgtqlvvkpniqnpepavyql
    kdprsqdstlclftdfdsqinvpktmesgtfitdktvldmkamdsksngaiawsnqtsft
    cqdif
    

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3c6lC (C:)
    ieadhvgtygisvyqspgdigqytfefdgdelfyvdldkketvwmlpefgqlasfdpqgg
    lqniavvkhnlgvltkrsnstpatneapqatvfpkspvllgqpntlicfvdnifppvini
    twlrnsksvadgvyetsffvnrdysfhklsyltfipsdddiydckvehwgleepvlkhwe
    pe
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >3c6lD (D:)
    feaqkakankavdggggslvprgsggggserhfvyqfmgecyftngtqriryvtryiynr
    eeyvrydsdvgehravtelgrpdaeywnsqpeilertraeldtvcrhnyegpethtslrr
    leqpnvvislsrtealnhhntlvcsvtdfypakikvrwfrngqeetvgvsstqlirngdw
    tfqvlvmlemtprrgevytchvehpslkspitvewka
    

    Sequence, based on observed residues (ATOM records): (download)
    >3c6lD (D:)
    feaqkakankavrhfvyqfmgecyftngtqriryvtryiynreeyvrydsdvgehravte
    lgrpdaeywnsqpeilertraeldtvcrhnyegpethtslrrleqpnvvislshntlvcs
    vtdfypakikvrwfrngqeetvgvsstqlirngdwtfqvlvmlemtprrgevytchvehp
    slkspitvewka
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >3c6lE (E:)
    qqvrqspqsltvwegetailncsyedstfdyfpwyhqfpgespalliairpvsnkkedgr
    ftiffnkrekkfslhiadsqpgdsatyfcaasdnriffgdgtqlvvkpniqnpepavyql
    kdprsqdstlclftdfdsqinvpktmesgtfitdktvldmkamdsksngaiawsnqtsft
    cqdif
    

    Sequence, based on observed residues (ATOM records): (download)
    >3c6lE (E:)
    qqvrqspqsltvwegetailncsyedstfdyfpwyhqfpgespalliairpvsnkkedgr
    ftiffnkrekkfslhiadsqpgdsatyfcaasdnriffgdgtqlvvkpniqnpepavyql
    kdprsqdstlclftdfdsqinvpktmesgtfitdktvldmkamdsksngaiawsnqtsft
    cqdi
    

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3c6lG (G:)
    ieadhvgtygisvyqspgdigqytfefdgdelfyvdldkketvwmlpefgqlasfdpqgg
    lqniavvkhnlgvltkrsnstpatneapqatvfpkspvllgqpntlicfvdnifppvini
    twlrnsksvadgvyetsffvnrdysfhklsyltfipsdddiydckvehwgleepvlkhwe
    pe
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >3c6lH (H:)
    feaqkakankavdggggslvprgsggggserhfvyqfmgecyftngtqriryvtryiynr
    eeyvrydsdvgehravtelgrpdaeywnsqpeilertraeldtvcrhnyegpethtslrr
    leqpnvvislsrtealnhhntlvcsvtdfypakikvrwfrngqeetvgvsstqlirngdw
    tfqvlvmlemtprrgevytchvehpslkspitvewka
    

    Sequence, based on observed residues (ATOM records): (download)
    >3c6lH (H:)
    feaqkakankavrhfvyqfmgecyftngtqriryvtryiynreeyvrydsdvgehravte
    lgrpdaeywnsqpeilertraeldtvcrhnyegpethtslrrleqpnvvislshntlvcs
    vtdfypakikvrwfrngqeetvgvsstqlirngdwtfqvlvmlemtprrgevytchvehp
    slkspitvewka