PDB entry 3c5l

View 3c5l on RCSB PDB site
Description: Polo-like kinase 1 Polo box domain in complex with PPHSpT peptide
Class: transferase
Keywords: Plk1, Polo-like kinase 1, Polo box domain, phosphopeptide, ATP-binding, Nucleotide-binding, Nucleus, Phosphoprotein, Serine/threonine-protein kinase, Transferase
Deposited on 2008-01-31, released 2009-02-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-08-25, with a file datestamp of 2009-08-21.
Experiment type: XRAY
Resolution: 2.33 Å
R-factor: 0.246
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase PLK1
    Species: Homo sapiens [TaxId:9606]
    Gene: PLK1, PLK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3c5la1, d3c5la2
  • Chain 'B':
    Compound: peptide
    Database cross-references and differences (RAF-indexed):
    • PDB 3C5L (0-4)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3c5lA (A:)
hlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkyglgyqlcdnsv
gvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnymsehllk
aganitpregdelarlpylrtwfrtrsaiilhlsngsvqinffqdhtklilcplmaavty
idekrdfrtyrlslleeygcckelasrlryartmvdkllss

    Sequence, based on observed residues (ATOM records): (download) 
    >3c5lA (A:)
hlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkyglgyqlcdnsv
gvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnymsehllk
aganitpregrlpylrtwfrtrsaiilhlsngsvqinffqdhtklilcplmaavtyidek
rdfrtyrlslleeygcckelasrlryartmvdkllss

  • Chain 'B':
    No sequence available.