PDB entry 3c5g

View 3c5g on RCSB PDB site
Description: Structure of a ternary complex of the R517K Pol lambda mutant
Class: Transferase/DNA, Lyase/DNA
Keywords: helix-hairpin-helix, DNA damage, DNA repair, DNA replication, DNA synthesis, DNA-binding, DNA-directed DNA polymerase, Lyase, Manganese, Metal-binding, Nucleotidyltransferase, Nucleus, Phosphoprotein, Polymorphism, Transferase, Transferase/DNA, Lyase/DNA COMPLEX
Deposited on 2008-01-31, released 2008-07-29
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.201
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase lambda
    Species: HOMO SAPIENS
    Gene: POLL
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UGP5 (Start-334)
      • engineered (276)
    Domains in SCOPe 2.05: d3c5ga1, d3c5ga2, d3c5ga3
  • Chain 'B':
    Compound: DNA polymerase lambda
    Species: HOMO SAPIENS
    Gene: POLL
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UGP5 (Start-334)
      • engineered (276)
    Domains in SCOPe 2.05: d3c5gb1, d3c5gb2, d3c5gb3
  • Chain 'D':
    Compound: DNA (5'-d(p*dgp*dcp*dcp*dg)-3')
  • Chain 'E':
    Compound: DNA (5'-d(p*dgp*dcp*dcp*dg)-3')
  • Chain 'P':
    Compound: DNA (5'-d(*dcp*dap*dgp*dtp*dap*(2dt))-3')
  • Chain 'Q':
    Compound: DNA (5'-d(*dcp*dap*dgp*dtp*dap*(2dt))-3')
  • Chain 'T':
    Compound: DNA (5'-d(*dcp*dgp*dgp*dcp*dap*dap*dtp*dap*dcp*dtp*dg)-3')
  • Chain 'U':
    Compound: DNA (5'-d(*dcp*dgp*dgp*dcp*dap*dap*dtp*dap*dcp*dtp*dg)-3')
  • Heterogens: MG, NA, EDO, D3T, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3c5gA (A:)
maqpssqkatnhnlhiteklevlakaysvqgdkwralgyakainalksfhkpvtsyqeac
sipgigkrmaekiieilesghlrkldhisesvpvlelfsniwgagtktaqmwyqqgfrsl
edirsqaslttqqaiglkhysdflermpreeateieqtvqkaaqafnsgllcvacgsyrr
gkatcgdvdvlithpdgrshrgifsrlldslrqegfltddlvsqeengqqqkylgvcrlp
gpgrrhrrldiivvpysefacallyftgsahfnrsmkalaktkgmslsehalstavvrnt
hgckvgpgrvlptptekdvfrllglpyrepaerdw

    Sequence, based on observed residues (ATOM records): (download) 
    >3c5gA (A:)
atnhnlhiteklevlakaysvqgdkwralgyakainalksfhkpvtsyqeacsipgigkr
maekiieilesghlrkldhisesvpvlelfsniwgagtktaqmwyqqgfrsledirsqas
lttqqaiglkhysdflermpreeateieqtvqkaaqafnsgllcvacgsyrrgkatcgdv
dvlithpdgrshrgifsrlldslrqegfltddlvsqeengqqqkylgvcrlpgpgrrhrr
ldiivvpysefacallyftgsahfnrsmkalaktkgmslsehalstavvhgckvgpgrvl
ptptekdvfrllglpyrepaerdw

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3c5gB (B:)
maqpssqkatnhnlhiteklevlakaysvqgdkwralgyakainalksfhkpvtsyqeac
sipgigkrmaekiieilesghlrkldhisesvpvlelfsniwgagtktaqmwyqqgfrsl
edirsqaslttqqaiglkhysdflermpreeateieqtvqkaaqafnsgllcvacgsyrr
gkatcgdvdvlithpdgrshrgifsrlldslrqegfltddlvsqeengqqqkylgvcrlp
gpgrrhrrldiivvpysefacallyftgsahfnrsmkalaktkgmslsehalstavvrnt
hgckvgpgrvlptptekdvfrllglpyrepaerdw

    Sequence, based on observed residues (ATOM records): (download) 
    >3c5gB (B:)
ssqkatnhnlhiteklevlakaysvqgdkwralgyakainalksfhkpvtsyqeacsipg
igkrmaekiieilesghlrkldhisesvpvlelfsniwgagtktaqmwyqqgfrsledir
sqaslttqqaiglkhysdflermpreeateieqtvqkaaqafnsgllcvacgsyrrgkat
cgdvdvlithpdgrshrgifsrlldslrqegfltddlvsqeengqqqkylgvcrlpgpgr
rhrrldiivvpysefacallyftgsahfnrsmkalaktkgmslsehalstavvrhgckvg
pgrvlptptekdvfrllglpyrepaerdw

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    No sequence available.

  • Chain 'T':
    No sequence available.

  • Chain 'U':
    No sequence available.