PDB entry 3c4o

View 3c4o on RCSB PDB site
Description: Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) E73M/S130K/S146M complex
Class: hydrolase/hydrolase inhibitor
Keywords: Beta-lactamase, Beta-lactamase inhibitory protein, protein-protein complex, BLIP, SHV-1, Antibiotic resistance, Hydrolase, Plasmid, Secreted, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Deposited on 2008-01-30, released 2008-05-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 1.7000000000000002 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase SHV-1
    Species: Klebsiella pneumoniae
    Gene: bla, shv1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3c4oa_
  • Chain 'B':
    Compound: Beta-lactamase inhibitory protein
    Species: Streptomyces clavuligerus
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35804 (0-164)
      • engineered (72)
      • engineered (129)
      • engineered (145)
    Domains in SCOPe 2.08: d3c4ob_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3c4oA (A:)
    spqpleqiklsesqlsgrvgmiemdlasgrtltawraderfpmmstfkvvlcgavlarvd
    agdeqlerkihyrqqdlvdyspvsekhladgmtvgelcaaaitmsdnsaanlllatvggp
    agltaflrqigdnvtrldrwetelnealpgdardtttpasmaatlrklltsqrlsarsqr
    qllqwmvddrvagplirsvlpagwfiadktgagergargivallgpnnkaerivviylrd
    tpasmaernqqiagigaaliehwqr
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3c4oB (B:)
    agvmtgakftqiqfgmtrqqvldiagaencetggsfgdsihcrghaagdyyayatfgfts
    aaadakvdsksqmkllapsaptltlakfnqvtvgmtraqvlatvgqgscttwseyypayp
    stagvtlslkcfdvdgysstgfyrgmahlwftdgvlqgkrqwdlv