PDB entry 3c3n

View 3c3n on RCSB PDB site
Description: Crystal structure of dihydroorotate dehydrogenase from Trypanosoma cruzi strain Y
Class: oxidoreductase
Keywords: DHODH, Trypanosoma cruzi strain Y, dihydroorotate dehydrogenase, pyrd, OXIDOREDUCTASE
Deposited on 2008-01-28, released 2008-04-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.206
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydroorotate dehydrogenase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: TCDHOD2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4D3W2 (0-End)
      • variant (60)
    Domains in SCOPe 2.08: d3c3na_
  • Chain 'B':
    Compound: dihydroorotate dehydrogenase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: TCDHOD2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4D3W2 (0-End)
      • variant (60)
    Domains in SCOPe 2.08: d3c3nb_
  • Chain 'C':
    Compound: dihydroorotate dehydrogenase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: TCDHOD2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4D3W2 (0-End)
      • variant (60)
    Domains in SCOPe 2.08: d3c3nc_
  • Chain 'D':
    Compound: dihydroorotate dehydrogenase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: TCDHOD2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4D3W2 (0-End)
      • variant (60)
    Domains in SCOPe 2.08: d3c3nd_
  • Heterogens: SO4, FMN, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3c3nA (A:)
clklnlldhvfanpfmnaagvlcsteedlrcmtasssgalvsksctsaprdgnpepryma
vplgsinsmglpnlgfdfylkyasdlhdyskkplflsisglsveenvamvrrlapvaqek
gvllelnlscpnvpgkpqvaydfeamrtylqqvslayglpfgvkmppyfdiahfdtaaav
lnefplvkfvtcvnsvgnglvidaesesvvikpkqgfgglggkyilptalanvnafyrrc
pdklvfgcggvysgedaflhilagasmvqvgtalqeegpgiftrledelleimarkgyrt
leefrgrvktie

    Sequence, based on observed residues (ATOM records): (download) 
    >3c3nA (A:)
clklnlldhvfanpfmnaagvlcsteedlrcmtasssgalvsksctsaprdgnpepryma
vplgsinsmglpnlgfdfylkyasdlhdyskkplflsisglsveenvamvrrlapvaqek
gvllelnlscpnvpgkpqvaydfeamrtylqqvslayglpfgvkmppyfdiahfdtaaav
lnefplvkfvtcvnsvgnglvidaesesvvikpkqgfgglggkyilptalanvnafyrrc
pdklvfgcggvysgedaflhilagasmvqvgtalqeegpgiftrledelleimarkgyrt
leefrgrvkti

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3c3nB (B:)
clklnlldhvfanpfmnaagvlcsteedlrcmtasssgalvsksctsaprdgnpepryma
vplgsinsmglpnlgfdfylkyasdlhdyskkplflsisglsveenvamvrrlapvaqek
gvllelnlscpnvpgkpqvaydfeamrtylqqvslayglpfgvkmppyfdiahfdtaaav
lnefplvkfvtcvnsvgnglvidaesesvvikpkqgfgglggkyilptalanvnafyrrc
pdklvfgcggvysgedaflhilagasmvqvgtalqeegpgiftrledelleimarkgyrt
leefrgrvktie

    Sequence, based on observed residues (ATOM records): (download) 
    >3c3nB (B:)
clklnlldhvfanpfmnaagvlcsteedlrcmtasssgalvsksctsaprdgnpepryma
vplgsinsmglpnlgfdfylkyasdlhdyskkplflsisglsveenvamvrrlapvaqek
gvllelnlscpnvpgkpqvaydfeamrtylqqvslayglpfgvkmppyfdiahfdtaaav
lnefplvkfvtcvnsvgnglvidaesesvvikpkqgfgglggkyilptalanvnafyrrc
pdklvfgcggvysgedaflhilagasmvqvgtalqeegpgiftrledelleimarkgyrt
leefrgrvkti

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3c3nC (C:)
clklnlldhvfanpfmnaagvlcsteedlrcmtasssgalvsksctsaprdgnpepryma
vplgsinsmglpnlgfdfylkyasdlhdyskkplflsisglsveenvamvrrlapvaqek
gvllelnlscpnvpgkpqvaydfeamrtylqqvslayglpfgvkmppyfdiahfdtaaav
lnefplvkfvtcvnsvgnglvidaesesvvikpkqgfgglggkyilptalanvnafyrrc
pdklvfgcggvysgedaflhilagasmvqvgtalqeegpgiftrledelleimarkgyrt
leefrgrvktie

    Sequence, based on observed residues (ATOM records): (download) 
    >3c3nC (C:)
clklnlldhvfanpfmnaagvlcsteedlrcmtasssgalvsksctsaprdgnpepryma
vplgsinsmglpnlgfdfylkyasdlhdyskkplflsisglsveenvamvrrlapvaqek
gvllelnlscpnvpgkpqvaydfeamrtylqqvslayglpfgvkmppyfdiahfdtaaav
lnefplvkfvtcvnsvgnglvidaesesvvikpkqgfgglggkyilptalanvnafyrrc
pdklvfgcggvysgedaflhilagasmvqvgtalqeegpgiftrledelleimarkgyrt
leefrgrvkti

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3c3nD (D:)
clklnlldhvfanpfmnaagvlcsteedlrcmtasssgalvsksctsaprdgnpepryma
vplgsinsmglpnlgfdfylkyasdlhdyskkplflsisglsveenvamvrrlapvaqek
gvllelnlscpnvpgkpqvaydfeamrtylqqvslayglpfgvkmppyfdiahfdtaaav
lnefplvkfvtcvnsvgnglvidaesesvvikpkqgfgglggkyilptalanvnafyrrc
pdklvfgcggvysgedaflhilagasmvqvgtalqeegpgiftrledelleimarkgyrt
leefrgrvktie

    Sequence, based on observed residues (ATOM records): (download) 
    >3c3nD (D:)
clklnlldhvfanpfmnaagvlcsteedlrcmtasssgalvsksctsaprdgnpepryma
vplgsinsmglpnlgfdfylkyasdlhdyskkplflsisglsveenvamvrrlapvaqek
gvllelnlscpnvpgkpqvaydfeamrtylqqvslayglpfgvkmppyfdiahfdtaaav
lnefplvkfvtcvnsvgnglvidaesesvvikpkqgfgglggkyilptalanvnafyrrc
pdklvfgcggvysgedaflhilagasmvqvgtalqeegpgiftrledelleimarkgyrt
leefrgrvkti