PDB entry 3c3b

View 3c3b on RCSB PDB site
Description: Crystal Structure of human phosphoglycerate kinase bound to D-CDP
Class: Transferase
Keywords: protein-nucleotide complex, D-enantiomer of CDP, kinase, Acetylation, ATP-binding, Cytoplasm, Disease mutation, Glycolysis, Hereditary hemolytic anemia, Nucleotide-binding, Phosphoprotein, Polymorphism, Transferase
Deposited on 2008-01-28, released 2008-07-01
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.171
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphoglycerate kinase 1
    Species: HOMO SAPIENS
    Gene: PGK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3c3ba_
  • Chain 'B':
    Compound: Phosphoglycerate kinase 1
    Species: HOMO SAPIENS
    Gene: PGK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3c3bb_
  • Heterogens: PO4, CDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3c3bA (A:)
gshmslsnkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaks
vvlmshlgrpdgvpmpdkyslepvavelksllgkdvlflkdcvgpevekacanpaagsvi
llenlrfhveeegkgkdasgnkvkaepakieafraslsklgdvyvndafgtahrahssmv
gvnlpqkaggflmkkelnyfakalesperpflailggakvadkiqlinnmldkvnemiig
ggmaftflkvlnnmeigtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenak
tgqatvasgipagwmgldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmd
evvkatsrgcitiigggdtatccakwntedkvshvstgggaslellegkvlpgvdalsni

    Sequence, based on observed residues (ATOM records): (download) 
    >3c3bA (A:)
slsnkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaksvvlm
shlgrpdgvpmpdkyslepvavelksllgkdvlflkdcvgpevekacanpaagsvillen
lrfhveeegkgkdasgnkvkaepakieafraslsklgdvyvndafgtahrahssmvgvnl
pqkaggflmkkelnyfakalesperpflailggakvadkiqlinnmldkvnemiigggma
ftflkvlnnmeigtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenaktgqa
tvasgipagwmgldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmdevvk
atsrgcitiiggdkvshvstgggaslellegkvlpgvdalsni

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3c3bB (B:)
gshmslsnkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaks
vvlmshlgrpdgvpmpdkyslepvavelksllgkdvlflkdcvgpevekacanpaagsvi
llenlrfhveeegkgkdasgnkvkaepakieafraslsklgdvyvndafgtahrahssmv
gvnlpqkaggflmkkelnyfakalesperpflailggakvadkiqlinnmldkvnemiig
ggmaftflkvlnnmeigtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenak
tgqatvasgipagwmgldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmd
evvkatsrgcitiigggdtatccakwntedkvshvstgggaslellegkvlpgvdalsni

    Sequence, based on observed residues (ATOM records): (download) 
    >3c3bB (B:)
lsnkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaksvvlms
hlgrpdgvpmpdkyslepvavelksllgkdvlflkdcvekacanpaagsvillenlrfhv
eeegkgkdasgnkvkaepakieafraslsklgdvyvndafgtahrahssmvgvnlpqkag
gflmkkelnyfakalesperpflailggakvadkiqlinnmldkvnemiigggmaftflk
vlnnmeigtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenaktgqatvasg
ipagwmgldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmdevvkatsrg
citiiggdkvshvstgggaslellegkvlpgvdalsni