PDB entry 3c3a

View 3c3a on RCSB PDB site
Description: Crystal Structure of human phosphoglycerate kinase bound to 3-phosphoglycerate and L-ADP
Class: Transferase
Keywords: protein-nucleotide complex, L-enantiomer of ADP, kinase, Acetylation, ATP-binding, Cytoplasm, Disease mutation, Glycolysis, Hereditary hemolytic anemia, Nucleotide-binding, Phosphoprotein, Polymorphism, Transferase
Deposited on 2008-01-28, released 2008-07-01
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.181
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphoglycerate kinase 1
    Species: HOMO SAPIENS
    Gene: PGK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3c3aa_
  • Chain 'B':
    Compound: Phosphoglycerate kinase 1
    Species: HOMO SAPIENS
    Gene: PGK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3c3ab_
  • Heterogens: MG, 3PG, ADP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3c3aA (A:)
    gshmslsnkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaks
    vvlmshlgrpdgvpmpdkyslepvavelksllgkdvlflkdcvgpevekacanpaagsvi
    llenlrfhveeegkgkdasgnkvkaepakieafraslsklgdvyvndafgtahrahssmv
    gvnlpqkaggflmkkelnyfakalesperpflailggakvadkiqlinnmldkvnemiig
    ggmaftflkvlnnmeigtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenak
    tgqatvasgipagwmgldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmd
    evvkatsrgcitiigggdtatccakwntedkvshvstgggaslellegkvlpgvdalsni
    

    Sequence, based on observed residues (ATOM records): (download)
    >3c3aA (A:)
    lsnkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaksvvlms
    hlgrpdgvpmpdkyslepvavelksllgkdvlflkdcvgpevekacanpaagsvillenl
    rfhveeegkgkdasgnkvkaepakieafraslsklgdvyvndafgtahrahssmvgvnlp
    qkaggflmkkelnyfakalesperpflailggakvadkiqlinnmldkvnemiigggmaf
    tflkvlnnmeigtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenaktgqat
    vasgipagwmgldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmdevvka
    tsrgcitiiggwntedkvshvstgggaslellegkvlpgvdalsni
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3c3aB (B:)
    gshmslsnkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaks
    vvlmshlgrpdgvpmpdkyslepvavelksllgkdvlflkdcvgpevekacanpaagsvi
    llenlrfhveeegkgkdasgnkvkaepakieafraslsklgdvyvndafgtahrahssmv
    gvnlpqkaggflmkkelnyfakalesperpflailggakvadkiqlinnmldkvnemiig
    ggmaftflkvlnnmeigtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenak
    tgqatvasgipagwmgldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmd
    evvkatsrgcitiigggdtatccakwntedkvshvstgggaslellegkvlpgvdalsni
    

    Sequence, based on observed residues (ATOM records): (download)
    >3c3aB (B:)
    lsnkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaksvvlms
    hlgrpdgvpmpdkyslepvavelksllgkdvlflkdcvkacanpaagsvillenlrfhve
    eegkgkdasgnkvkaepakieafraslsklgdvyvndafgtahrahssmvgvnlpqkagg
    flmkkelnyfakalesperpflailggakvadkiqlinnmldkvnemiigggmaftflkv
    lnnmeigtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenaktgqatvasgi
    pagwmgldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmdevvkatsrgc
    itiiggedkvshvstgggaslellegkvlpgvdalsni