PDB entry 3c1t

View 3c1t on RCSB PDB site
Description: Binding of two substrate analogue molecules to dihydroflavonol 4-reductase alters the functional geometry of the catalytic site
Class: oxidoreductase
Keywords: short chain dehydrogenase reductase, Rossmann fold, flavonoids, OXIDOREDUCTASE
Deposited on 2008-01-24, released 2008-02-19
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.189
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydroflavonol 4-reductase
    Species: Vitis vinifera [TaxId:29760]
    Gene: DFR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3c1ta_
  • Chain 'B':
    Compound: dihydroflavonol 4-reductase
    Species: Vitis vinifera [TaxId:29760]
    Gene: DFR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3c1tb_
  • Chain 'C':
    Compound: dihydroflavonol 4-reductase
    Species: Vitis vinifera [TaxId:29760]
    Gene: DFR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3c1tc_
  • Chain 'D':
    Compound: dihydroflavonol 4-reductase
    Species: Vitis vinifera [TaxId:29760]
    Gene: DFR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3c1td_
  • Heterogens: NAP, MYC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3c1tA (A:)
mgsqsetvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltl
wkadladegsfdeaikgctgvfhvatpmdfeskdpenevikptiegmlgimkscaaaktv
rrlvftssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyake
nnidfitiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiy
lfenpkaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdl
gfefkysledmftgavdtcrakgllppshekpvdgkt

    Sequence, based on observed residues (ATOM records): (download) 
    >3c1tA (A:)
etvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltlwkadl
adegsfdeaikgctgvfhvatpmkdpenevikptiegmlgimkscaaaktvrrlvftssa
gtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyakennidfitii
ptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiylfenpkaeg
ryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdlgfefkysle
dmftgavdtcrakgllppsh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3c1tB (B:)
mgsqsetvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltl
wkadladegsfdeaikgctgvfhvatpmdfeskdpenevikptiegmlgimkscaaaktv
rrlvftssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyake
nnidfitiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiy
lfenpkaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdl
gfefkysledmftgavdtcrakgllppshekpvdgkt

    Sequence, based on observed residues (ATOM records): (download) 
    >3c1tB (B:)
mgsqsetvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltl
wkadladegsfdeaikgctgvfhvatpmskdpenevikptiegmlgimkscaaaktvrrl
vftssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyakenni
dfitiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiylfe
npkaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdlgfe
fkysledmftgavdtcrakgllppsh

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3c1tC (C:)
mgsqsetvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltl
wkadladegsfdeaikgctgvfhvatpmdfeskdpenevikptiegmlgimkscaaaktv
rrlvftssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyake
nnidfitiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiy
lfenpkaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdl
gfefkysledmftgavdtcrakgllppshekpvdgkt

    Sequence, based on observed residues (ATOM records): (download) 
    >3c1tC (C:)
etvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltlwkadl
adegsfdeaikgctgvfhvatpmdfeskdpenevikptiegmlgimkscaaaktvrrlvf
tssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyakennidf
itiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiylfenp
kaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdlgfefk
ysledmftgavdtcrakgllppshe

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3c1tD (D:)
mgsqsetvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltl
wkadladegsfdeaikgctgvfhvatpmdfeskdpenevikptiegmlgimkscaaaktv
rrlvftssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyake
nnidfitiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiy
lfenpkaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdl
gfefkysledmftgavdtcrakgllppshekpvdgkt

    Sequence, based on observed residues (ATOM records): (download) 
    >3c1tD (D:)
etvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltlwkadl
adegsfdeaikgctgvfhvatpmskdpenevikptiegmlgimkscaaaktvrrlvftss
agtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyakennidfiti
iptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiylfenpkae
gryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdlgfefkysl
edmftgavdtcrakgllppsh