PDB entry 3c0o

View 3c0o on RCSB PDB site
Description: Crystal structure of the proaerolysin mutant Y221G complexed with mannose-6-phosphate
Class: toxin
Keywords: toxin, cytolytic toxin, pore-forming toxin
Deposited on 2008-01-21, released 2008-02-12
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-10-02, with a file datestamp of 2013-09-27.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.207
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aerolysin
    Species: Aeromonas hydrophila [TaxId:644]
    Gene: aerA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09167
      • engineered (220)
    Domains in SCOPe 2.05: d3c0oa1, d3c0oa2
  • Chain 'B':
    Compound: Aerolysin
    Species: Aeromonas hydrophila [TaxId:644]
    Gene: aerA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09167
      • engineered (220)
    Domains in SCOPe 2.05: d3c0ob1, d3c0ob2
  • Heterogens: ACT, M6P, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3c0oA (A:)
aepvypdqlrlfslgqgvcgdkyrpvnreeaqsvksnivgmmgqwqisglangwvimgpg
yngeikpgtasntwcyptnpvtgeiptlsaldipdgdevdvqwrlvhdsanfikptsyla
hylgyawvggnhsqyvgedmdvtrdgdgwvirgnndggcdgyrcgdktaikvsnfaynld
pdsfkhgdvtqsdrqlvktvvgwavndsdtpqsgydvtlrgdtatnwsktntyglsekvt
tknkfkwplvgetelsieiaanqswasqnggstttslsqsvrptvparskipvkielyka
disypyefkadvsydltlsgflrwggnawythpdnrpnwnhtfvigpykdkassiryqwd
kryipgevkwwdwnwtiqqnglstmqnnlarvlrpvragitgdfsaesqfagnieigapv
plaadskvrrarsvdgagqglrleipldaqelsglgfnnvslsvtpaanq

    Sequence, based on observed residues (ATOM records): (download) 
    >3c0oA (A:)
epvypdqlrlfslgqgvcgdkyrpvnreeaqsvksnivgmmgqwqisglangwvimgpgy
ngeikpgtasntwcyptnpvtgeiptlsaldipdgdevdvqwrlvhdsanfikptsylah
ylgyawvggnhsqyvgedmdvtrdgdgwvirgnndggcdgyrcgdktaikvsnfaynldp
dsfkhgdvtqsdrqlvktvvgwavndsdtpqsgydvtlrgdtatnwsktntyglsekvtt
knkfkwplvgetelsieiaanqswasqnggstttslsqsvrptvparskipvkielykad
isypyefkadvsydltlsgflrwggnawythpdnrpnwnhtfvigpykdkassiryqwdk
ryipgevkwwdwnwtiqqnglstmqnnlarvlrpvragitgdfsaesqfagnieigapvp
lglrleipldaqelsglgfnnvslsvtpaa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3c0oB (B:)
aepvypdqlrlfslgqgvcgdkyrpvnreeaqsvksnivgmmgqwqisglangwvimgpg
yngeikpgtasntwcyptnpvtgeiptlsaldipdgdevdvqwrlvhdsanfikptsyla
hylgyawvggnhsqyvgedmdvtrdgdgwvirgnndggcdgyrcgdktaikvsnfaynld
pdsfkhgdvtqsdrqlvktvvgwavndsdtpqsgydvtlrgdtatnwsktntyglsekvt
tknkfkwplvgetelsieiaanqswasqnggstttslsqsvrptvparskipvkielyka
disypyefkadvsydltlsgflrwggnawythpdnrpnwnhtfvigpykdkassiryqwd
kryipgevkwwdwnwtiqqnglstmqnnlarvlrpvragitgdfsaesqfagnieigapv
plaadskvrrarsvdgagqglrleipldaqelsglgfnnvslsvtpaanq

    Sequence, based on observed residues (ATOM records): (download) 
    >3c0oB (B:)
epvypdqlrlfslgqgvcgdkyrpvnreeaqsvksnivgmmgqwqisglangwvimgpgy
ngeikpgtasntwcyptnpvtgeiptlsaldipdgdevdvqwrlvhdsanfikptsylah
ylgyawvggnhsqyvgedmdvtrdgdgwvirgnndggcdgyrcgdktaikvsnfaynldp
dsfkhgdvtqsdrqlvktvvgwavndsdtpqsgydvtlrgdtatnwsktntyglsekvtt
knkfkwplvgetelsieiaanqswasqnggstttslsqsvrptvparskipvkielykad
isypyefkadvsydltlsgflrwggnawythpdnrpnwnhtfvigpykdkassiryqwdk
ryipgevkwwdwnwtiqqnglstmqnnlarvlrpvragitgdfsaesqfagnieigapvp
lglrleipldaqelsglgfnnvslsvtpaa