PDB entry 3bze

View 3bze on RCSB PDB site
Description: The human non-classical major histocompatibility complex molecule HLA-E
Class: immune system
Keywords: MHC fold, Transmembrane, Disease mutation, Glycation, Glycoprotein, Immune response, Immunoglobulin domain, MHC I, Pyrrolidone carboxylic acid, Secreted, IMMUNE SYSTEM
Deposited on 2008-01-17, released 2008-04-29
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.245
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, alpha chain E
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3bzea1, d3bzea2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.03: d3bzeb_
  • Chain 'C':
    Compound: HLA class I histocompatibility antigen, alpha chain E
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3bzec1, d3bzec2
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.03: d3bzed_
  • Chain 'E':
    Compound: HLA class I histocompatibility antigen, alpha chain E
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3bzee1, d3bzee2
  • Chain 'F':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.03: d3bzef_
  • Chain 'G':
    Compound: HLA class I histocompatibility antigen, alpha chain E
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3bzeg1, d3bzeg2
  • Chain 'H':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.03: d3bzeh_
  • Chain 'P':
    Compound: leader peptide of HLA class I histocompatibility antigen, alpha chain G
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'Q':
    Compound: leader peptide of HLA class I histocompatibility antigen, alpha chain G
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'R':
    Compound: leader peptide of HLA class I histocompatibility antigen, alpha chain G
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'S':
    Compound: leader peptide of HLA class I histocompatibility antigen, alpha chain G
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3bzeA (A:)
    shslkyfhtsvsrpgrgeprfisvgyvddtqfvrfdndaasprmvprapwmeqegseywd
    retrsardtaqifrvnlrtlrgyynqseagshtlqwmhgcelgpdrrflrgyeqfaydgk
    dyltlnedlrswtavdtaaqiseqksndaseaehqrayledtcvewlhkylekgketllh
    leppkthvthhpisdheatlrcwalgfypaeitltwqqdgeghtqdtelvetrpagdgtf
    qkwaavvvpsgeeqrytchvqheglpepvtlrw
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3bzeB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3bzeC (C:)
    shslkyfhtsvsrpgrgeprfisvgyvddtqfvrfdndaasprmvprapwmeqegseywd
    retrsardtaqifrvnlrtlrgyynqseagshtlqwmhgcelgpdrrflrgyeqfaydgk
    dyltlnedlrswtavdtaaqiseqksndaseaehqrayledtcvewlhkylekgketllh
    leppkthvthhpisdheatlrcwalgfypaeitltwqqdgeghtqdtelvetrpagdgtf
    qkwaavvvpsgeeqrytchvqheglpepvtlrw
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3bzeD (D:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >3bzeE (E:)
    shslkyfhtsvsrpgrgeprfisvgyvddtqfvrfdndaasprmvprapwmeqegseywd
    retrsardtaqifrvnlrtlrgyynqseagshtlqwmhgcelgpdrrflrgyeqfaydgk
    dyltlnedlrswtavdtaaqiseqksndaseaehqrayledtcvewlhkylekgketllh
    leppkthvthhpisdheatlrcwalgfypaeitltwqqdgeghtqdtelvetrpagdgtf
    qkwaavvvpsgeeqrytchvqheglpepvtlrw
    

    Sequence, based on observed residues (ATOM records): (download)
    >3bzeE (E:)
    shslkyfhtsvsrpgrgeprfisvgyvddtqfvrfdndaasprmvprapwmeqegseywd
    retrsardtaqifrvnlrtlrgyynqseagshtlqwmhgcelgpdrrflrgyeqfaydgk
    dyltlnedlrswtavdtaaqiseqksndaseaehqrayledtcvewlhkylekgketllh
    leppkthvthhpisdheatlrcwalgfypaeitltwqqdgtelvetrpagdgtfqkwaav
    vvpsgeeqrytchvqheglpepvtlrw
    

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3bzeF (F:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3bzeG (G:)
    shslkyfhtsvsrpgrgeprfisvgyvddtqfvrfdndaasprmvprapwmeqegseywd
    retrsardtaqifrvnlrtlrgyynqseagshtlqwmhgcelgpdrrflrgyeqfaydgk
    dyltlnedlrswtavdtaaqiseqksndaseaehqrayledtcvewlhkylekgketllh
    leppkthvthhpisdheatlrcwalgfypaeitltwqqdgeghtqdtelvetrpagdgtf
    qkwaavvvpsgeeqrytchvqheglpepvtlrw
    

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3bzeH (H:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    No sequence available.

  • Chain 'R':
    No sequence available.

  • Chain 'S':
    No sequence available.