PDB entry 3bz3

View 3bz3 on RCSB PDB site
Description: Crystal Structure Analysis of Focal Adhesion Kinase with a Methanesulfonamide Diaminopyrimidine Inhibitor
Class: transferase
Keywords: kinase, DFG-helix, Acetylation, Alternative splicing, ATP-binding, Cell junction, Nucleotide-binding, Phosphoprotein, Transferase, Tyrosine-protein kinase
Deposited on 2008-01-17, released 2008-04-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Focal adhesion kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PTK2, FAK, FAK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3bz3a_
  • Heterogens: YAM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3bz3A (A:)
dyeiqrerielgrcigegqfgdvhqgiymspenpalavaiktcknctsdsvrekflqeal
tmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyayqlsta
layleskrfvhrdiaarnvlvssndcvklgdfglsrymedstyykaskgklpikwmapes
infrrftsasdvwmfgvcmweilmhgvkpfqgvknndvigriengerlpmppncpptlys
lmtkcwaydpsrrprftelkaqlstileeekaqqee

    Sequence, based on observed residues (ATOM records): (download) 
    >3bz3A (A:)
dyeiqrerielgrcigegqfgdvhqgiymsplavaiktcknctsdsvrekflqealtmrq
fdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyayqlstalayl
eskrfvhrdiaarnvlvssndcvklgdfglsrylpikwmapesinfrrftsasdvwmfgv
cmweilmhgvkpfqgvknndvigriengerlpmppncpptlyslmtkcwaydpsrrprft
elkaqlstileeekaqqee