PDB entry 3bz0

View 3bz0 on RCSB PDB site
Description: Lactobacillus Casei Thymidylate Synthase Ternary Complex with DUMP and the Phtalimidic Derivative C00
Class: transferase
Keywords: NUCLEOTIDE SYNTHASE, STRUCTURE BASED DRUG DESIGN, Methyltransferase, Nucleotide biosynthesis, Transferase
Deposited on 2008-01-17, released 2009-01-20
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-07-24, with a file datestamp of 2013-07-19.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.235
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Lactobacillus casei [TaxId:1582]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3bz0a_
  • Heterogens: UMP, C00, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3bz0A (A:)
    mleqpyldlakkvldeghfkpdrthtgtysifghqmrfdlskgfpllttkkvpfglikse
    llwflhgdtnirfllqhrnhiwdewafekwvksdeyhgpdmtdfghrsqkdpefaavyhe
    emakfddrvlhddafaakygdlglvygsqwrawhtskgdtidqlgdvieqikthpysrrl
    ivsawnpedvptmalppchtlyqfyvndgklslqlyqrsadiflgvpfniasyallthlv
    ahecglevgefihtfgdahlyvnhldqikeqlsrtprpaptlqlnpdkhdifdfdmkdik
    llnydpypaikapvav
    

    Sequence, based on observed residues (ATOM records): (download)
    >3bz0A (A:)
    mleqpyldlakkvldeghfkpdrthtgtysifghqmrfdlskgfpllttkkvpfglikse
    llwflhgdtnirfllqhrnhiwdewafekwvksdeydmtdfghrsqkfaavyheemakfd
    drvlhddafaakygdlglvygsqwrawhtskgdtidqlgdvieqikthpysrrlivsawn
    pedvptmalppchtlyqfyvndgklslqlyqrsadiflgvpfniasyallthlvahecgl
    evgefihtfgdahlyvnhldqikeqlsrtprpaptlqlnpdkhdifdfdmkdikllnydp
    ypaika