PDB entry 3bys

View 3bys on RCSB PDB site
Description: co-crystal structure of Lck and aminopyrimidine amide 10b
Class: transferase
Keywords: Lck, Kinase domain, Alternative splicing, ATP-binding, Chromosomal rearrangement, Cytoplasm, Disease mutation, Host-virus interaction, Lipoprotein, Membrane, Myristate, Nucleotide-binding, Palmitate, Phosphoprotein, Proto-oncogene, SH2 domain, SH3 domain, Transferase, Tyrosine-protein kinase
Deposited on 2008-01-16, released 2008-09-16
The last revision prior to the SCOP 1.75 freeze date was dated 2008-12-30, with a file datestamp of 2008-12-26.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.246
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Proto-oncogene tyrosine-protein kinase LCK
    Species: Homo sapiens [TaxId:9606]
    Gene: LCK
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d3bysa1
  • Heterogens: AM5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3bysA (A:)
qtqkpqkpwwedewevpretlklverlgagqfgevwmgyynghtkvavkslkqgsmspda
flaeanlmkqlqhqrlvrlyavvtqepiyiiteymengslvdflktpsgikltinklldm
aaqiaegmafieernyihrdlraanilvsdtlsckiadfglarliedneytaregakfpi
kwtapeainygtftiksdvwsfgillteivthgripypgmtnpeviqnlergyrmvrpdn
cpeelyqlmrlcwkerpedrptfdylrsvledfftat

    Sequence, based on observed residues (ATOM records): (download) 
    >3bysA (A:)
qkpwwedewevpretlklverlgagqfgevwmgyynghtkvavkslkqgsmspdaflaea
nlmkqlqhqrlvrlyavvtqepiyiiteymengslvdflktpsgikltinklldmaaqia
egmafieernyihrdlraanilvsdtlsckiadfglpikwtapeainygtftiksdvwsf
gillteivthgripypgmtnpeviqnlergyrmvrpdncpeelyqlmrlcwkerpedrpt
fdylrsvledfftat