PDB entry 3bxx

View 3bxx on RCSB PDB site
Description: Binding of two substrate analogue molecules to dihydroflavonol 4-reductase alters the functional geometry of the catalytic site
Class: oxidoreductase
Keywords: rossmann fold, OXIDOREDUCTASE
Deposited on 2008-01-15, released 2008-10-21
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-20.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.292
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydroflavonol 4-reductase
    Species: Vitis vinifera [TaxId:29760]
    Gene: DFR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3bxxa_
  • Chain 'B':
    Compound: dihydroflavonol 4-reductase
    Species: Vitis vinifera [TaxId:29760]
    Gene: DFR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3bxxb_
  • Chain 'C':
    Compound: dihydroflavonol 4-reductase
    Species: Vitis vinifera [TaxId:29760]
    Gene: DFR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3bxxc_
  • Chain 'D':
    Compound: dihydroflavonol 4-reductase
    Species: Vitis vinifera [TaxId:29760]
    Gene: DFR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3bxxd_
  • Chain 'E':
    Compound: dihydroflavonol 4-reductase
    Species: Vitis vinifera [TaxId:29760]
    Gene: DFR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3bxxe_
  • Chain 'F':
    Compound: dihydroflavonol 4-reductase
    Species: Vitis vinifera [TaxId:29760]
    Gene: DFR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3bxxf_
  • Heterogens: NAP, QUE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3bxxA (A:)
mgsqsetvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltl
wkadladegsfdeaikgctgvfhvatpmdfeskdpenevikptiegmlgimkscaaaktv
rrlvftssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyake
nnidfitiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiy
lfenpkaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdl
gfefkysledmftgavdtcrakgllppshekpvdgkt

    Sequence, based on observed residues (ATOM records): (download) 
    >3bxxA (A:)
etvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltlwkadl
adegsfdeaikgctgvfhvatpmdfeskdpenevikptiegmlgimkscaaaktvrrlvf
tssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyakennidf
itiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiylfenp
kaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdlgfefk
ysledmftgavdtcrakgllppsh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3bxxB (B:)
mgsqsetvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltl
wkadladegsfdeaikgctgvfhvatpmdfeskdpenevikptiegmlgimkscaaaktv
rrlvftssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyake
nnidfitiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiy
lfenpkaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdl
gfefkysledmftgavdtcrakgllppshekpvdgkt

    Sequence, based on observed residues (ATOM records): (download) 
    >3bxxB (B:)
etvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltlwkadl
adegsfdeaikgctgvfhvatpmdfeskdpenevikptiegmlgimkscaaaktvrrlvf
tssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyakennidf
itiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiylfenp
kaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdlgfefk
ysledmftgavdtcrakgllppsh

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3bxxC (C:)
mgsqsetvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltl
wkadladegsfdeaikgctgvfhvatpmdfeskdpenevikptiegmlgimkscaaaktv
rrlvftssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyake
nnidfitiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiy
lfenpkaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdl
gfefkysledmftgavdtcrakgllppshekpvdgkt

    Sequence, based on observed residues (ATOM records): (download) 
    >3bxxC (C:)
etvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltlwkadl
adegsfdeaikgctgvfhvatpmdfeskdpenevikptiegmlgimkscaaaktvrrlvf
tssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyakennidf
itiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiylfenp
kaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdlgfefk
ysledmftgavdtcrakgllppsh

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3bxxD (D:)
mgsqsetvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltl
wkadladegsfdeaikgctgvfhvatpmdfeskdpenevikptiegmlgimkscaaaktv
rrlvftssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyake
nnidfitiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiy
lfenpkaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdl
gfefkysledmftgavdtcrakgllppshekpvdgkt

    Sequence, based on observed residues (ATOM records): (download) 
    >3bxxD (D:)
etvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltlwkadl
adegsfdeaikgctgvfhvatpmdfeskdpenevikptiegmlgimkscaaaktvrrlvf
tssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyakennidf
itiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiylfenp
kaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdlgfefk
ysledmftgavdtcrakgllppsh

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3bxxE (E:)
mgsqsetvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltl
wkadladegsfdeaikgctgvfhvatpmdfeskdpenevikptiegmlgimkscaaaktv
rrlvftssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyake
nnidfitiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiy
lfenpkaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdl
gfefkysledmftgavdtcrakgllppshekpvdgkt

    Sequence, based on observed residues (ATOM records): (download) 
    >3bxxE (E:)
etvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltlwkadl
adegsfdeaikgctgvfhvatpmdfeskdpenevikptiegmlgimkscaaaktvrrlvf
tssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyakennidf
itiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiylfenp
kaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdlgfefk
ysledmftgavdtcrakgllppsh

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3bxxF (F:)
mgsqsetvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltl
wkadladegsfdeaikgctgvfhvatpmdfeskdpenevikptiegmlgimkscaaaktv
rrlvftssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyake
nnidfitiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiy
lfenpkaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdl
gfefkysledmftgavdtcrakgllppshekpvdgkt

    Sequence, based on observed residues (ATOM records): (download) 
    >3bxxF (F:)
etvcvtgasgfigswlvmrllergytvratvrdptnvkkvkhlldlpkaethltlwkadl
adegsfdeaikgctgvfhvatpmdfeskdpenevikptiegmlgimkscaaaktvrrlvf
tssagtvniqehqlpvydescwsdmefcrakkmtawmyfvsktlaeqaawkyakennidf
itiiptlvvgpfimssmppslitalspitgneahysiirqgqfvhlddlcnahiylfenp
kaegryicsshdciildlakmlrekypeyniptefkgvdenlksvcfsskkltdlgfefk
ysledmftgavdtcrakgllppsh