PDB entry 3bxn

View 3bxn on RCSB PDB site
Description: The high resolution crystal structure of HLA-B*1402 complexed with a Cathepsin A signal sequence peptide, pCatA
Class: immune system
Keywords: Major Histocompatibility Complex, MHC, Human Leokocyte Antigen, HLA, HLA-B14, HLA-B*1402, HLA-B1402, HLA-B*14, pCatA, Cathepsin A, Ankylosing Spondylitis, Autoimmunity, IMMUNE SYSTEM
Deposited on 2008-01-14, released 2009-02-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.86 Å
R-factor: 0.172
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: HLA-B*1402 extracellular domain
  Species: Homo sapiens [TaxId:9606]
  Gene: HLA-B
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q56H30 (1-End)
• Chain 'B':
  Compound: Beta-2-microglobulin
  Species: Homo sapiens [TaxId:9606]
  Gene: B2M
  Database cross-references and differences (RAF-indexed):
  • Uniprot P61769 (1-99)
  Domains in SCOPe 2.08: d3bxnb_
• Chain 'C':
  Compound: Cathepsin A signal sequence octapeptide
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • Uniprot P10619 (0-8)
• Heterogens: GOL, HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  Sequence, based on SEQRES records: (download)
  

  >3bxnB (B:)
  miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
  wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >3bxnB (B:)
  iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
  sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  
• Chain 'C':
  No sequence available.