PDB entry 3bwf

View 3bwf on RCSB PDB site
Description: Crystal structure of the human Pim1 in complex with an osmium compound
Class: transferase
Keywords: TRANSFERASE, PIM1, Kinase, ATP-binding, Phosphorylation, Alternative initiation, Cytoplasm, Manganese, Membrane, Metal-binding, Nucleotide-binding, Nucleus, Phosphoprotein, Proto-oncogene, Serine/threonine-protein kinase
Deposited on 2008-01-09, released 2008-06-24
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.171
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Proto-oncogene serine/threonine-protein kinase Pim-1
    Species: HOMO SAPIENS
    Gene: PIM1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11309
      • engineered (249)
    Domains in SCOPe 2.05: d3bwfa_
  • Heterogens: SO4, DWC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3bwfA (A:)
    mllskinslahlraapcndlhatklapgkekeplesqyqvgpllgsggfgsvysgirvsd
    nlpvaikhvekdrisdwgelpngtrvpmevvllkkvssgfsgvirlldwferpdsfvlil
    erpepvqdlfdfitergalqeelarsffwqvleavrhchncgvlhrdikdenilidlnrg
    elklidfgsgallkdtvytdfdgtrvysppewiryhryhgrsaavwslgillydmvcgdi
    pfehdeeiiggqvffrqrvssecqhlirwclalrpsdrptfeeiqnhpwmqdvllpqeta
    eihlhslspgpsk
    

    Sequence, based on observed residues (ATOM records): (download)
    >3bwfA (A:)
    plesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdrisdwgelpngtrvpmevvl
    lkkvssgfsgvirlldwferpdsfvlilerpepvqdlfdfitergalqeelarsffwqvl
    eavrhchncgvlhrdikdenilidlnrgelklidfgsgallkdtvytdfdgtrvysppew
    iryhryhgrsaavwslgillydmvcgdipfehdeeiiggqvffrqrvssecqhlirwcla
    lrpsdrptfeeiqnhpwmqdvllpqetaeihlh