PDB entry 3bw9

View 3bw9 on RCSB PDB site
Description: Crystal Structure of HLA B*3508 in complex with a HCMV 12-mer peptide from the pp65 protein
Class: immune system
Keywords: HLA B*3508, crystal structure, HCMV, pp65, immunology, Glycoprotein, Host-virus interaction, Immune response, Membrane, MHC I, Polymorphism, Transmembrane, Ubl conjugation, Disease mutation, Glycation, Immunoglobulin domain, Pyrrolidone carboxylic acid, Secreted, Phosphoprotein, Tegument protein, Viral matrix protein, Virion, IMMUNE SYSTEM
Deposited on 2008-01-08, released 2008-04-22
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.192
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, B-35 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30685 (0-275)
      • see remark 999 (155)
    Domains in SCOPe 2.06: d3bw9a1, d3bw9a2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.06: d3bw9b2, d3bw9b3
  • Chain 'C':
    Compound: CPS peptide from 65 kDa lower matrix phosphoprotein
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3bw9A (A:)
    gshsmryfytamsrpgrgeprfiavgyvddtqfvrfdsdaasprteprapwieqegpeyw
    drntqifktntqtyreslrnlrgyynqseagshiiqrmygcdlgpdgrllrghdqsaydg
    kdyialnedlsswtaadtaaqitqrkweaarvaeqrrayleglcvewlrrylengketlq
    radppkthvthhpvsdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrt
    fqkwaavvvpsgeeqrytchvqheglpkpltlrwep
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3bw9B (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.