PDB entry 3bva

View 3bva on RCSB PDB site
Description: Cystal structure of HIV-1 Active Site Mutant D25N and p2-NC analog inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: DRUG RESISTANCE, HIV-1, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2008-01-05, released 2008-04-01
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.05 Å
R-factor: 0.155
AEROSPACI score: 0.95 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Protease (Retropepsin)
  Species: Human immunodeficiency virus 1 [TaxId:11676]
  Gene: gag-pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
    • engineered (6)
    • engineered (24)
    • engineered (32)
    • engineered (62)
    • engineered (66)
    • engineered (94)
  Domains in SCOPe 2.05: d3bvaa_
• Chain 'B':
  Compound: Protease (Retropepsin)
  Species: Human immunodeficiency virus 1 [TaxId:11676]
  Gene: gag-pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
    • engineered (6)
    • engineered (24)
    • engineered (32)
    • engineered (62)
    • engineered (66)
    • engineered (94)
  Domains in SCOPe 2.05: d3bvab_
• Heterogens: 2NC, GOL, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3bvaA (A:)
  pqitlwkrplvtikiggqlkeallntgaddtvieemslpgrwkpkmiggiggfikvrqyd
  qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3bvaB (B:)
  pqitlwkrplvtikiggqlkeallntgaddtvieemslpgrwkpkmiggiggfikvrqyd
  qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf