PDB entry 3bun
View 3bun on RCSB PDB site
Description: Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Sprouty4
Class: ligase/signaling protein
Keywords: Cbl, TKB, ligase, signal transduction, proto-oncogene, complex, Alternative splicing, Cytoplasm, Developmental protein, Membrane, Calcium, Metal-binding, Phosphoprotein, SH2 domain, Ubl conjugation pathway, Zinc, Zinc-finger, LIGASE/SIGNALING PROTEIN COMPLEX
Deposited on
2008-01-03, released
2008-02-26
The last revision prior to the SCOPe 2.06 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.201
AEROSPACI score: 0.42
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: 13-meric peptide from Portein sprouty homolog 4
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: E3 ubiquitin-protein ligase CBL
Species: Homo sapiens [TaxId:9606]
Gene: CBL, CBL2, RNF55
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3bunb1, d3bunb2, d3bunb3 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3bunB (B:)
gsliglmkdafqphhhhhhhlsphppgtvdkkmvekcwklmdkvvrlcqnpklalknspp
yildllpdtyqhlrtilsryegkmetlgeneyfrvfmenlmkktkqtislfkegkermye
ensqprrnltklslifshmlaelkgifpsglfqgdtfritkadaaefwrkafgektivpw
ksfrqalhevhpissgleamalkstidltcndyisvfefdiftrlfqpwssllrnwnsla
vthpgymafltydevkarlqkfihkpgsyifrlsctrlgqwaigyvtadgnilqtiphnk
plfqalidgfregfylfpdgrnqnpdltg
Sequence, based on observed residues (ATOM records): (download)
>3bunB (B:)
pgtvdkkmvekcwklmdkvvrlcqnpklalknsppyildllpdtyqhlrtilsryegkme
tlgeneyfrvfmenlmkktkqtislfkegkermyeensqprrnltklslifshmlaelkg
ifpsglfqgdtfritkadaaefwrkafgektivpwksfrqalhevhpissgleamalkst
idltcndyisvfefdiftrlfqpwssllrnwnslavthpgymafltydevkarlqkfihk
pgsyifrlsctrlgqwaigyvtadgnilqtiphnkplfqalidgfregfylfpdgrnqnp
dltg