PDB entry 3buk

View 3buk on RCSB PDB site
Description: Crystal Structure of the Neurotrophin-3 and p75NTR Symmetrical Complex
Class: signaling protein
Keywords: Ligand-receptor complex, BETA-sheet, Neurotrophin-3, p75NTR, Cleavage on pair of basic residues, Glycoprotein, Growth factor, Secreted, Apoptosis, Developmental protein, Differentiation, Membrane, Neurogenesis, Transmembrane, SIGNALING PROTEIN
Deposited on 2008-01-02, released 2008-07-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.227
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neurotrophin-3
    Species: HOMO SAPIENS
    Gene: NT-3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3buka_
  • Chain 'B':
    Compound: Neurotrophin-3
    Species: HOMO SAPIENS
    Gene: NT-3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3bukb_
  • Chain 'C':
    Compound: Tumor necrosis factor receptor superfamily member 16
    Species: Rattus norvegicus
    Gene: Ngfr, Tnfrsf16
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07174 (Start-160)
      • engineered (41)
    Domains in SCOPe 2.07: d3bukc1, d3bukc2, d3bukc3, d3bukc4
  • Chain 'D':
    Compound: Tumor necrosis factor receptor superfamily member 16
    Species: Rattus norvegicus
    Gene: Ngfr, Tnfrsf16
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07174 (Start-160)
      • engineered (41)
    Domains in SCOPe 2.07: d3bukd1, d3bukd2, d3bukd3, d3bukd4
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3bukA (A:)
    yaehkshrgeysvcdseslwvtdkssaidirghqvtvlgeiktgnspvkqyfyetrckea
    rpvkngcrgiddkhwnsqcktsqtyvraltsennklvgwrwiridtscvcalsrkigrt
    

    Sequence, based on observed residues (ATOM records): (download)
    >3bukA (A:)
    kshrgeysvcdseslwvtdkssaidirghqvtvlgeiktgnspvkqyfyetrckearpvk
    ngcrgiddkhwnsqcktsqtyvraltsennklvgwrwiridtscvcalsrk
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3bukB (B:)
    yaehkshrgeysvcdseslwvtdkssaidirghqvtvlgeiktgnspvkqyfyetrckea
    rpvkngcrgiddkhwnsqcktsqtyvraltsennklvgwrwiridtscvcalsrkigrt
    

    Sequence, based on observed residues (ATOM records): (download)
    >3bukB (B:)
    kshrgeysvcdseslwvtdkssaidirghqvtvlgeiktgnspvkqyfyetrckearpvk
    ngcrgiddkhwnsqcktsqtyvraltsennklvgwrwiridtscvcalsrk
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >3bukC (C:)
    ketcstglythsgecckacnlgegvaqpcganqtvcepcldsvtfsdvvsatepckpcte
    clglqsmsapcveaddavcrcaygyyqdeetghceacsvcevgsglvfscqdkqntvcee
    cpegtysdeanhvdpclpctvcedterqlrectpwadaecehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >3bukC (C:)
    tcstglythsgecckacnlgegvaqpcganqtvcepcldsvtfsdvvsatepckpctecl
    glqsmsapcveaddavcrcaygyyqdeetghceacsvcevgsglvfscqdkqntvceecp
    egtysdeanhvdpclpctvcedterqlrectpwadaece
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >3bukD (D:)
    ketcstglythsgecckacnlgegvaqpcganqtvcepcldsvtfsdvvsatepckpcte
    clglqsmsapcveaddavcrcaygyyqdeetghceacsvcevgsglvfscqdkqntvcee
    cpegtysdeanhvdpclpctvcedterqlrectpwadaecehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >3bukD (D:)
    tcstglythsgecckacnlgegvaqpcganqtvcepcldsvtfsdvvsatepckpctecl
    glqsmsapcveaddavcrcaygyyqdeetghceacsvcevgsglvfscqdkqntvceecp
    egtysdeanhvdpclpctvcedterqlrectpwadaece