PDB entry 3buk
View 3buk on RCSB PDB site
Description: Crystal Structure of the Neurotrophin-3 and p75NTR Symmetrical Complex
Class: signaling protein
Keywords: Ligand-receptor complex, BETA-sheet, Neurotrophin-3, p75NTR, Cleavage on pair of basic residues, Glycoprotein, Growth factor, Secreted, Apoptosis, Developmental protein, Differentiation, Membrane, Neurogenesis, Transmembrane, SIGNALING PROTEIN
Deposited on
2008-01-02, released
2008-07-15
The last revision prior to the SCOP 1.75 freeze date was dated
2008-08-26, with a file datestamp of
2008-08-22.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.227
AEROSPACI score: 0.24
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Neurotrophin-3
Species: HOMO SAPIENS
Gene: NT-3
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d3buka1 - Chain 'B':
Compound: Neurotrophin-3
Species: HOMO SAPIENS
Gene: NT-3
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d3bukb1 - Chain 'C':
Compound: Tumor necrosis factor receptor superfamily member 16
Species: Rattus norvegicus
Gene: Ngfr, Tnfrsf16
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d3bukc1, d3bukc2, d3bukc3, d3bukc4 - Chain 'D':
Compound: Tumor necrosis factor receptor superfamily member 16
Species: Rattus norvegicus
Gene: Ngfr, Tnfrsf16
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d3bukd1, d3bukd2, d3bukd3, d3bukd4 - Heterogens: NAG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3bukA (A:)
yaehkshrgeysvcdseslwvtdkssaidirghqvtvlgeiktgnspvkqyfyetrckea
rpvkngcrgiddkhwnsqcktsqtyvraltsennklvgwrwiridtscvcalsrkigrt
Sequence, based on observed residues (ATOM records): (download)
>3bukA (A:)
kshrgeysvcdseslwvtdkssaidirghqvtvlgeiktgnspvkqyfyetrckearpvk
ngcrgiddkhwnsqcktsqtyvraltsennklvgwrwiridtscvcalsrk
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3bukB (B:)
yaehkshrgeysvcdseslwvtdkssaidirghqvtvlgeiktgnspvkqyfyetrckea
rpvkngcrgiddkhwnsqcktsqtyvraltsennklvgwrwiridtscvcalsrkigrt
Sequence, based on observed residues (ATOM records): (download)
>3bukB (B:)
kshrgeysvcdseslwvtdkssaidirghqvtvlgeiktgnspvkqyfyetrckearpvk
ngcrgiddkhwnsqcktsqtyvraltsennklvgwrwiridtscvcalsrk
- Chain 'C':
Sequence, based on SEQRES records: (download)
>3bukC (C:)
ketcstglythsgecckacnlgegvaqpcganqtvcepcldsvtfsdvvsatepckpcte
clglqsmsapcveaddavcrcaygyyqdeetghceacsvcevgsglvfscqdkqntvcee
cpegtysdeanhvdpclpctvcedterqlrectpwadaecehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>3bukC (C:)
tcstglythsgecckacnlgegvaqpcganqtvcepcldsvtfsdvvsatepckpctecl
glqsmsapcveaddavcrcaygyyqdeetghceacsvcevgsglvfscqdkqntvceecp
egtysdeanhvdpclpctvcedterqlrectpwadaece
- Chain 'D':
Sequence, based on SEQRES records: (download)
>3bukD (D:)
ketcstglythsgecckacnlgegvaqpcganqtvcepcldsvtfsdvvsatepckpcte
clglqsmsapcveaddavcrcaygyyqdeetghceacsvcevgsglvfscqdkqntvcee
cpegtysdeanhvdpclpctvcedterqlrectpwadaecehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>3bukD (D:)
tcstglythsgecckacnlgegvaqpcganqtvcepcldsvtfsdvvsatepckpctecl
glqsmsapcveaddavcrcaygyyqdeetghceacsvcevgsglvfscqdkqntvceecp
egtysdeanhvdpclpctvcedterqlrectpwadaece