PDB entry 3buk

View 3buk on RCSB PDB site
Description: Crystal Structure of the Neurotrophin-3 and p75NTR Symmetrical Complex
Class: signaling protein
Keywords: Ligand-receptor complex, BETA-sheet, Neurotrophin-3, p75NTR, Cleavage on pair of basic residues, Glycoprotein, Growth factor, Secreted, Apoptosis, Developmental protein, Differentiation, Membrane, Neurogenesis, Transmembrane, SIGNALING PROTEIN
Deposited on 2008-01-02, released 2008-07-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neurotrophin-3
    Species: HOMO SAPIENS
    Gene: NT-3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3buka_
  • Chain 'B':
    Compound: Neurotrophin-3
    Species: HOMO SAPIENS
    Gene: NT-3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3bukb_
  • Chain 'C':
    Compound: Tumor necrosis factor receptor superfamily member 16
    Species: Rattus norvegicus
    Gene: Ngfr, Tnfrsf16
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07174 (Start-160)
      • engineered (41)
    Domains in SCOPe 2.08: d3bukc1, d3bukc2, d3bukc3, d3bukc4
  • Chain 'D':
    Compound: Tumor necrosis factor receptor superfamily member 16
    Species: Rattus norvegicus
    Gene: Ngfr, Tnfrsf16
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07174 (Start-160)
      • engineered (41)
    Domains in SCOPe 2.08: d3bukd1, d3bukd2, d3bukd3, d3bukd4
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3bukA (A:)
yaehkshrgeysvcdseslwvtdkssaidirghqvtvlgeiktgnspvkqyfyetrckea
rpvkngcrgiddkhwnsqcktsqtyvraltsennklvgwrwiridtscvcalsrkigrt

    Sequence, based on observed residues (ATOM records): (download) 
    >3bukA (A:)
kshrgeysvcdseslwvtdkssaidirghqvtvlgeiktgnspvkqyfyetrckearpvk
ngcrgiddkhwnsqcktsqtyvraltsennklvgwrwiridtscvcalsrk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3bukB (B:)
yaehkshrgeysvcdseslwvtdkssaidirghqvtvlgeiktgnspvkqyfyetrckea
rpvkngcrgiddkhwnsqcktsqtyvraltsennklvgwrwiridtscvcalsrkigrt

    Sequence, based on observed residues (ATOM records): (download) 
    >3bukB (B:)
kshrgeysvcdseslwvtdkssaidirghqvtvlgeiktgnspvkqyfyetrckearpvk
ngcrgiddkhwnsqcktsqtyvraltsennklvgwrwiridtscvcalsrk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3bukC (C:)
ketcstglythsgecckacnlgegvaqpcganqtvcepcldsvtfsdvvsatepckpcte
clglqsmsapcveaddavcrcaygyyqdeetghceacsvcevgsglvfscqdkqntvcee
cpegtysdeanhvdpclpctvcedterqlrectpwadaecehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3bukC (C:)
tcstglythsgecckacnlgegvaqpcganqtvcepcldsvtfsdvvsatepckpctecl
glqsmsapcveaddavcrcaygyyqdeetghceacsvcevgsglvfscqdkqntvceecp
egtysdeanhvdpclpctvcedterqlrectpwadaece

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3bukD (D:)
ketcstglythsgecckacnlgegvaqpcganqtvcepcldsvtfsdvvsatepckpcte
clglqsmsapcveaddavcrcaygyyqdeetghceacsvcevgsglvfscqdkqntvcee
cpegtysdeanhvdpclpctvcedterqlrectpwadaecehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3bukD (D:)
tcstglythsgecckacnlgegvaqpcganqtvcepcldsvtfsdvvsatepckpctecl
glqsmsapcveaddavcrcaygyyqdeetghceacsvcevgsglvfscqdkqntvceecp
egtysdeanhvdpclpctvcedterqlrectpwadaece