PDB entry 3br5

View 3br5 on RCSB PDB site
Description: Crystal Structure of the Complex of Rhodamine 6G Bound to QacR(E90Q), a Mutant of a Multidrug Binding Transcriptional Repressor
Class: transcription
Keywords: QacR, multidrug resistance, TetR, Rhodamine 6G, DNA-binding, Plasmid, Repressor, Transcription, Transcription regulation
Deposited on 2007-12-20, released 2008-12-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2008-12-23, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.244
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HTH-type transcriptional regulator qacR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: qacR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N3
      • engineered (66)
      • engineered (89)
      • engineered (140)
    Domains in SCOPe 2.08: d3br5a1, d3br5a2
  • Chain 'B':
    Compound: HTH-type transcriptional regulator qacR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: qacR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N3
      • engineered (66)
      • engineered (89)
      • engineered (140)
    Domains in SCOPe 2.08: d3br5b1, d3br5b2
  • Chain 'D':
    Compound: HTH-type transcriptional regulator qacR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: qacR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N3
      • engineered (66)
      • engineered (89)
      • engineered (140)
    Domains in SCOPe 2.08: d3br5d1, d3br5d2
  • Chain 'E':
    Compound: HTH-type transcriptional regulator qacR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: qacR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N3
      • engineered (66)
      • engineered (89)
      • engineered (140)
    Domains in SCOPe 2.08: d3br5e1, d3br5e2
  • Heterogens: SO4, RHQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3br5A (A:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkseqikcktnrekfylynelslttqyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3br5A (A:)
nlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskw
qeqwkseqikcktnrekfylynelslttqyyyplqnaiiefyteyyktnsinekmnklen
kyidayhvifkegnlngewsindvnavskiaanavngivtftqnineriklmnkfsqifl
ngls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3br5B (B:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkseqikcktnrekfylynelslttqyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3br5B (B:)
lkdkilgvakelfikngynatttgeivklsesskgnlyfktkenlfleilnieeskwqeq
wkseqikcktnrekfylynelslttqyyyplqnaiiefyteyktnsinekmnklenkyid
ayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsqiflng
ls

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3br5D (D:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkseqikcktnrekfylynelslttqyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3br5D (D:)
kdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskwqe
qwkseqikcktnrekfylynelslttqyyyplqnaiiefyteyyktnsinekmnklenky
idayhvifkegnlngewsindvnavskiaanavngivtfteqnineriklmnkfsqifln
gls

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3br5E (E:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkseqikcktnrekfylynelslttqyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3br5E (E:)
nlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskw
qeqwkseqikcktnrekfylynelslttqyyyplqnaiiefyteyyktnsinekmnklen
kyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsqi
flngls