PDB entry 3bp4
View 3bp4 on RCSB PDB site
Description: The high resolution crystal structure of HLA-B*2705 in complex with a Cathepsin A signal sequence peptide pCatA
Class: immune system
Keywords: Major Histocompatibility Complex, MHC, Human Leukocyte Antigen, HLA, Beta-2-microglobulin, b2m, Cathepsin A, pCatA, Ankylosing Spondylitis, Glycoprotein, Host-virus interaction, Immune response, Membrane, MHC I, Transmembrane, Disease mutation, Glycation, Immunoglobulin domain, Pyrrolidone carboxylic acid, Secreted, Carboxypeptidase, Hydrolase, Lysosome, Protease, Zymogen, IMMUNE SYSTEM
Deposited on
2007-12-18, released
2008-12-23
The last revision prior to the SCOPe 2.02 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-25.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.175
AEROSPACI score: 0.52
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: HLA class I histocompatibility antigen, B-27 alpha chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: Beta-2-microglobulin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P61769 (1-99)
- initiating methionine (0)
Domains in SCOPe 2.02: d3bp4b_ - Chain 'C':
Compound: nonameric peptide from Lysosomal protective protein
Species: HOMO SAPIENS, synthetic [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Heterogens: GOL, HOH