PDB entry 3bnz

View 3bnz on RCSB PDB site
Description: Crystal structure of Thymidylate Synthase ternary complex with dUMP and 8A inhibitor
Class: transferase
Keywords: Thymidylate Synthase, Methyltransferase, Nucleotide biosynthesis, Transferase
Deposited on 2007-12-15, released 2008-12-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-07-24, with a file datestamp of 2013-07-19.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.219
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Lactobacillus casei [TaxId:1582]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3bnza_
  • Heterogens: PO4, UMP, C16, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3bnzA (A:)
mleqpyldlakkvldeghfkpdrthtgtysifghqmrfdlskgfpllttkkvpfglikse
llwflhgdtnirfllqhrnhiwdewafekwvksdeyhgpdmtdfghrsqkdpefaavyhe
emakfddrvlhddafaakygdlglvygsqwrawhtskgdtidqlgdvieqikthpysrrl
ivsawnpedvptmalppchtlyqfyvndgklslqlyqrsadiflgvpfniasyallthlv
ahecglevgefihtfgdahlyvnhldqikeqlsrtprpaptlqlnpdkhdifdfdmkdik
llnydpypaikapvav

    Sequence, based on observed residues (ATOM records): (download) 
    >3bnzA (A:)
mleqpyldlakkvldeghfkpdrthtgtysifghqmrfdlskgfpllttkkvpfglikse
llwflhgdtnirfllqhrnhiwdewafekwvksdeyhgdmtfghrsqkdpefaavyheem
akfddrvlhddafaakygdlglvygsqwrawhtskgdtidqlgdvieqikthpysrrliv
sawnpedvptmalppchtlyqfyvndgklslqlyqrsadiflgvpfniasyallthlvah
ecglevgefihtfgdahlyvnhldqikeqlsrtprpaptlqlnpdkhdifdfdmkdikll
nydpypaikapv