PDB entry 3bmc

View 3bmc on RCSB PDB site
Description: Structure of Pteridine Reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and substrate (folate)
Class: Oxidoreductase
Keywords: pteridine reductase, ptr1, trypanosoma brucei, short chain dehydrogenase, substrate, folate, Oxidoreductase
Deposited on 2007-12-13, released 2008-12-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.192
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pteridine reductase
    Species: Trypanosoma brucei brucei [TaxId:5702]
    Gene: PTR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3bmca_
  • Chain 'B':
    Compound: pteridine reductase
    Species: Trypanosoma brucei brucei [TaxId:5702]
    Gene: PTR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3bmcb_
  • Chain 'C':
    Compound: pteridine reductase
    Species: Trypanosoma brucei brucei [TaxId:5702]
    Gene: PTR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3bmcc_
  • Chain 'D':
    Compound: pteridine reductase
    Species: Trypanosoma brucei brucei [TaxId:5702]
    Gene: PTR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3bmcd_
  • Heterogens: NAP, FOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3bmcA (A:)
mgsshhhhhhssglvprgshmeapaavvtgaakrigraiavklhqtgyrvvihyhnsaea
avsladelnkersntavvcqadltnsnvlpasceeiinscfrafgrcdvlvnnasafypt
plvqgdhednsngktvetqvaeligtnaiapflltmsfaqrqkgtnpnctssnlsivnlc
damvdqpcmafslynmgkhalvgltqsaalelapygirvngvapgvsllpvamgeeekdk
wrrkvplgrreasaeqiadaviflvsgsaqyitgsiikvdgglslvha

    Sequence, based on observed residues (ATOM records): (download) 
    >3bmcA (A:)
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvgktvetqvaeligtnaia
pflltmsfaqrqsnlsivnlcdamvdqpcmafslynmgkhalvgltqsaalelapygirv
ngvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadaviflvsgsaqyitgsiikv
dgglslvha

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3bmcB (B:)
mgsshhhhhhssglvprgshmeapaavvtgaakrigraiavklhqtgyrvvihyhnsaea
avsladelnkersntavvcqadltnsnvlpasceeiinscfrafgrcdvlvnnasafypt
plvqgdhednsngktvetqvaeligtnaiapflltmsfaqrqkgtnpnctssnlsivnlc
damvdqpcmafslynmgkhalvgltqsaalelapygirvngvapgvsllpvamgeeekdk
wrrkvplgrreasaeqiadaviflvsgsaqyitgsiikvdgglslvha

    Sequence, based on observed residues (ATOM records): (download) 
    >3bmcB (B:)
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvgktvetqvaeligtnaia
pflltmsfaqrqnlsivnlcdamvdqpcmafslynmgkhalvgltqsaalelapygirvn
gvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadaviflvsgsaqyitgsiikvd
gglslvha

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3bmcC (C:)
mgsshhhhhhssglvprgshmeapaavvtgaakrigraiavklhqtgyrvvihyhnsaea
avsladelnkersntavvcqadltnsnvlpasceeiinscfrafgrcdvlvnnasafypt
plvqgdhednsngktvetqvaeligtnaiapflltmsfaqrqkgtnpnctssnlsivnlc
damvdqpcmafslynmgkhalvgltqsaalelapygirvngvapgvsllpvamgeeekdk
wrrkvplgrreasaeqiadaviflvsgsaqyitgsiikvdgglslvha

    Sequence, based on observed residues (ATOM records): (download) 
    >3bmcC (C:)
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvgktvetqvaeligtnaia
pflltmsfaqrqnlsivnlcdamvdqpcmafslynmgkhalvgltqsaalelapygirvn
gvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadaviflvsgsaqyitgsiikvd
gglslvha

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3bmcD (D:)
mgsshhhhhhssglvprgshmeapaavvtgaakrigraiavklhqtgyrvvihyhnsaea
avsladelnkersntavvcqadltnsnvlpasceeiinscfrafgrcdvlvnnasafypt
plvqgdhednsngktvetqvaeligtnaiapflltmsfaqrqkgtnpnctssnlsivnlc
damvdqpcmafslynmgkhalvgltqsaalelapygirvngvapgvsllpvamgeeekdk
wrrkvplgrreasaeqiadaviflvsgsaqyitgsiikvdgglslvha

    Sequence, based on observed residues (ATOM records): (download) 
    >3bmcD (D:)
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvgktvetqvaeligtnaia
pflltmsfaqrqsnlsivnlcdamvdqpcmafslynmgkhalvgltqsaalelapygirv
ngvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadaviflvsgsaqyitgsiikv
dgglslvha