SCOPe 2.08: Structural Classification of Proteins

PDB entry 3blx

View 3blx on RCSB PDB site
Description: Yeast Isocitrate Dehydrogenase (Apo Form)
Class: oxidoreductase
Keywords: TCA cycle, oxidative metabolism, allostery, dehydrogenase, decarboxylase, Allosteric enzyme, Magnesium, Manganese, Metal-binding, Mitochondrion, NAD, Oxidoreductase, RNA-binding, Transit peptide, Tricarboxylic acid cycle, Phosphoprotein
Deposited on 2007-12-11, released 2008-02-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.241
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Isocitrate dehydrogenase [NAD] subunit 1
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: IDH1
Database cross-references and differences (RAF-indexed):
- Uniprot P28834 (Start-348)
Domains in SCOPe 2.08: d3blxa_
Chain 'B':
Compound: Isocitrate dehydrogenase [NAD] subunit 2
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: IDH2
Database cross-references and differences (RAF-indexed):
- Uniprot P28241 (Start-353)
Domains in SCOPe 2.08: d3blxb_
Chain 'C':
Compound: Isocitrate dehydrogenase [NAD] subunit 1
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: IDH1
Database cross-references and differences (RAF-indexed):
- Uniprot P28834 (Start-348)
Domains in SCOPe 2.08: d3blxc_
Chain 'D':
Compound: Isocitrate dehydrogenase [NAD] subunit 2
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: IDH2
Database cross-references and differences (RAF-indexed):
- Uniprot P28241 (Start-353)
Domains in SCOPe 2.08: d3blxd_
Chain 'E':
Compound: Isocitrate dehydrogenase [NAD] subunit 1
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: IDH1
Database cross-references and differences (RAF-indexed):
- Uniprot P28834 (Start-348)
Domains in SCOPe 2.08: d3blxe_
Chain 'F':
Compound: Isocitrate dehydrogenase [NAD] subunit 2
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: IDH2
Database cross-references and differences (RAF-indexed):
- Uniprot P28241 (Start-353)
Domains in SCOPe 2.08: d3blxf_
Chain 'G':
Compound: Isocitrate dehydrogenase [NAD] subunit 1
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: IDH1
Database cross-references and differences (RAF-indexed):
- Uniprot P28834 (Start-348)
Domains in SCOPe 2.08: d3blxg_
Chain 'H':
Compound: Isocitrate dehydrogenase [NAD] subunit 2
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: IDH2
Database cross-references and differences (RAF-indexed):
- Uniprot P28241 (Start-353)
Domains in SCOPe 2.08: d3blxh_
Chain 'I':
Compound: Isocitrate dehydrogenase [NAD] subunit 1
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: IDH1
Database cross-references and differences (RAF-indexed):
- Uniprot P28834 (Start-348)
Domains in SCOPe 2.08: d3blxi_
Chain 'J':
Compound: Isocitrate dehydrogenase [NAD] subunit 2
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: IDH2
Database cross-references and differences (RAF-indexed):
- Uniprot P28241 (Start-353)
Domains in SCOPe 2.08: d3blxj_
Chain 'K':
Compound: Isocitrate dehydrogenase [NAD] subunit 1
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: IDH1
Database cross-references and differences (RAF-indexed):
- Uniprot P28834 (Start-348)
Domains in SCOPe 2.08: d3blxk_
Chain 'L':
Compound: Isocitrate dehydrogenase [NAD] subunit 2
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: IDH2
Database cross-references and differences (RAF-indexed):
- Uniprot P28241 (Start-353)
Domains in SCOPe 2.08: d3blxl_
Chain 'M':
Compound: Isocitrate dehydrogenase [NAD] subunit 1
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: IDH1
Database cross-references and differences (RAF-indexed):
- Uniprot P28834 (Start-348)
Domains in SCOPe 2.08: d3blxm_
Chain 'N':
Compound: Isocitrate dehydrogenase [NAD] subunit 2
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: IDH2
Database cross-references and differences (RAF-indexed):
- Uniprot P28241 (Start-353)
Domains in SCOPe 2.08: d3blxn_
Chain 'O':
Compound: Isocitrate dehydrogenase [NAD] subunit 1
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: IDH1
Database cross-references and differences (RAF-indexed):
- Uniprot P28834 (Start-348)
Domains in SCOPe 2.08: d3blxo_
Chain 'P':
Compound: Isocitrate dehydrogenase [NAD] subunit 2
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: IDH2
Database cross-references and differences (RAF-indexed):
- Uniprot P28241 (Start-353)
Domains in SCOPe 2.08: d3blxp_

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>3blxA (A:)
ataaqaertlpkkyggrftvtlipgdgvgkeitdsvrtifeaenipidwetinikqtdhk
egvyeaveslkrnkiglkglwhtpadqtghgslnvalrkqldiyanvalfkslkgvktri
pdidlivirentegefsglehesvpgvveslkvmtrpkteriarfafdfakkynrksvta
vhkanimklgdglfrniiteigqkeypdidvssiivdnasmqavakphqfdvlvtpsmyg
tilgnigaaliggpglvaganfgrdyavfepgsrhvgldikgqnvanptamilsstlmln
hlglneyatriskavhetiaegkhttrdiggsssttdftneiinklstm