PDB entry 3blt

View 3blt on RCSB PDB site
Description: Crystal structures of YopH complexed with PVSN and PVS, inhibitors of YopH which co-valent bind to Cys of active site
Class: hydrolase
Keywords: Co-valent binding, binding affinity, binding selectivity, Hydrolase, Membrane, Outer membrane, Plasmid, Protein phosphatase, Secreted, Virulence
Deposited on 2007-12-11, released 2009-02-10
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-10, with a file datestamp of 2009-02-06.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.18
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein phosphatase yopH
    Species: Yersinia enterocolitica [TaxId:630]
    Gene: yopH, yop51
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15273 (Start-304)
      • conflict (71)
    Domains in SCOPe 2.06: d3blta_
  • Heterogens: PSY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3bltA (A:)
rerphtsghhgagearatapstvspygpearaelssrlttlrntlapatndprylqacgg
eklnrfrdiqcrrqtavradlnanyiqvgntrtiacqyplqsqleshfrmlaenrtpvla
vlassseianqrfgmpdyfrqsgtygsitveskmtqqvglgdgimadmytltireagqkt
isvpvvhvgnwpdqtavssevtkalaslvdqtaetkrnmyeskgssavaddsklrpvihc
ragvgrtaqligamcmndsrnsqlsvedmvsqmrvqrngimvqkdeqldvliklaegqgr
pllns

    Sequence, based on observed residues (ATOM records): (download) 
    >3bltA (A:)
spygpearaelssrlttlrntlapatndprylqacggeklnrfrdiqcrrqtavradlna
nyiqvgntrtiacqyplqsqleshfrmlaenrtpvlavlassseianqrfgmpdyfrqsg
tygsitveskmtqqvglgdgimadmytltireagqktisvpvvhvgnwpdqtavssevtk
alaslvdqtaetkrnmyeskgssavaddsklrpvihcragvgrtaqligamcmndsrnsq
lsvedmvsqmrvqrngimvqkdeqldvliklaegqgrpllns