PDB entry 3bla

View 3bla on RCSB PDB site
Description: Synthetic Gene Encoded DcpS bound to inhibitor DG153249
Class: hydrolase
Keywords: MRNA DECAPPING ENZYME, DCPS, LIGAND COMPLEX, Cytoplasm, Hydrolase, Nonsense-mediated mRNA decay, Nucleus, Polymorphism, Structural Genomics, PSI-2, Protein Structure Initiative, Accelerated Technologies Center for Gene to 3D Structure, ATCG3D
Deposited on 2007-12-10, released 2008-10-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-10-06, with a file datestamp of 2009-10-02.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.213
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Scavenger mRNA-decapping enzyme DcpS
    Species: Homo sapiens [TaxId:9606]
    Gene: DCPS, DCS1, HINT5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3blaa1, d3blaa2
  • Chain 'B':
    Compound: Scavenger mRNA-decapping enzyme DcpS
    Species: Homo sapiens [TaxId:9606]
    Gene: DCPS, DCS1, HINT5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3blab1, d3blab2
  • Heterogens: DD3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3blaA (A:)
sapvrlpfsgfrlqkvlresardkiiflhgkvneasgdgdgedavvilektpfqveqvaq
lltgspelqlqfsndiystyhlfpprqlndvkttvvypatekhlqkylrqdlrliretgd
dyrnitlphlesqslsiqwvynildkkaeadrivfenpdpsdgfvlipdlkwnqqqlddl
yliaichrrgirslrdltpehlpllrnilhqgqeailqryrmkgdhlrvylhylpsyyhl
hvhftalgfeapgsgverahllaevienlecdprhyqqrtltfalraddpllkllqeaqq
s

    Sequence, based on observed residues (ATOM records): (download) 
    >3blaA (A:)
lpfsgfrlqkvlresardkiiflhgkvneedavvilektpfqveqvaqlltgspelqlqf
sndiystyhlfpprqlndvkttvvypatekhlqkylrqdlrliretgddyrnitlphles
qslsiqwvynildkkaeadrivfenpdpsdgfvlipdlkwnqqqlddlyliaichrrgir
slrdltpehlpllrnilhqgqeailqryrmkgdhlrvylhylpsyyhlhvhftalgfeap
gsgverahllaevienlecdprhyqqrtltfalraddpllkllqea

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3blaB (B:)
sapvrlpfsgfrlqkvlresardkiiflhgkvneasgdgdgedavvilektpfqveqvaq
lltgspelqlqfsndiystyhlfpprqlndvkttvvypatekhlqkylrqdlrliretgd
dyrnitlphlesqslsiqwvynildkkaeadrivfenpdpsdgfvlipdlkwnqqqlddl
yliaichrrgirslrdltpehlpllrnilhqgqeailqryrmkgdhlrvylhylpsyyhl
hvhftalgfeapgsgverahllaevienlecdprhyqqrtltfalraddpllkllqeaqq
s

    Sequence, based on observed residues (ATOM records): (download) 
    >3blaB (B:)
vrlpfsgfrlqkvlresardkiiflhgkvnedavvilektpfqveqvaqlltgspelqlq
fsndiystyhlfpprqlndvkttvvypatekhlqkylrqdlrliretgddyrnitlphle
sqslsiqwvynildkkaeadrivfenpdpsdgfvlipdlkwnqqqlddlyliaichrrgi
rslrdltpehlpllrnilhqgqeailqryrmkgdhlrvylhylpsyyhlhvhftalgfea
pgsgverahllaevienlecdprhyqqrtltfalraddpllkllqeaqq