PDB entry 3bl9

View 3bl9 on RCSB PDB site
Description: Synthetic Gene Encoded DcpS bound to inhibitor DG157493
Class: hydrolase
Keywords: MRNA DECAPPING ENZYME, DCPS, LIGAND COMPLEX, Cytoplasm, Hydrolase, Nonsense-mediated mRNA decay, Nucleus, Polymorphism, Structural Genomics, PSI-2, Protein Structure Initiative, Accelerated Technologies Center for Gene to 3D Structure, ATCG3D
Deposited on 2007-12-10, released 2008-10-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Scavenger mRNA-decapping enzyme DcpS
    Species: Homo sapiens [TaxId:9606]
    Gene: DCPS, DCS1, HINT5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3bl9a1, d3bl9a2
  • Chain 'B':
    Compound: Scavenger mRNA-decapping enzyme DcpS
    Species: Homo sapiens [TaxId:9606]
    Gene: DCPS, DCS1, HINT5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3bl9b1, d3bl9b2
  • Heterogens: DD2, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3bl9A (A:)
sapvrlpfsgfrlqkvlresardkiiflhgkvneasgdgdgedavvilektpfqveqvaq
lltgspelqlqfsndiystyhlfpprqlndvkttvvypatekhlqkylrqdlrliretgd
dyrnitlphlesqslsiqwvynildkkaeadrivfenpdpsdgfvlipdlkwnqqqlddl
yliaichrrgirslrdltpehlpllrnilhqgqeailqryrmkgdhlrvylhylpsyyhl
hvhftalgfeapgsgverahllaevienlecdprhyqqrtltfalraddpllkllqeaqq
s

    Sequence, based on observed residues (ATOM records): (download) 
    >3bl9A (A:)
lpfsgfrlqkvlresardkiiflhgkvneedavvilektpfqveqvaqlltgspelqlqf
sndiystyhlfpprqlndvkttvvypatekhlqkylrqdlrliretgddyrnitlphles
qslsiqwvynildkkaeadrivfenpdpsdgfvlipdlkwnqqqlddlyliaichrrgir
slrdltpehlpllrnilhqgqeailqryrmkgdhlrvylhylpsyyhlhvhftalgfeap
gsgverahllaevienlecdprhyqqrtltfalraddpllkllqea

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3bl9B (B:)
sapvrlpfsgfrlqkvlresardkiiflhgkvneasgdgdgedavvilektpfqveqvaq
lltgspelqlqfsndiystyhlfpprqlndvkttvvypatekhlqkylrqdlrliretgd
dyrnitlphlesqslsiqwvynildkkaeadrivfenpdpsdgfvlipdlkwnqqqlddl
yliaichrrgirslrdltpehlpllrnilhqgqeailqryrmkgdhlrvylhylpsyyhl
hvhftalgfeapgsgverahllaevienlecdprhyqqrtltfalraddpllkllqeaqq
s

    Sequence, based on observed residues (ATOM records): (download) 
    >3bl9B (B:)
vrlpfsgfrlqkvlresardkiiflhgkvnedavvilektpfqveqvaqlltgspelqlq
fsndiystyhlfpprqlndvkttvvypatekhlqkylrqdlrliretgddyrnitlphle
sqslsiqwvynildkkaeadrivfenpdpsdgfvlipdlkwnqqqlddlyliaichrrgi
rslrdltpehlpllrnilhqgqeailqryrmkgdhlrvylhylpsyyhlhvhftalgfea
pgsgverahllaevienlecdprhyqqrtltfalraddpllkllqeaqq