PDB entry 3bju

View 3bju on RCSB PDB site
Description: Crystal Structure of tetrameric form of human lysyl-tRNA synthetase
Class: ligase
Keywords: tRNA synthetase, Lysyl-tRNA, Aminoacyl-tRNA synthetase, ATP-binding, Cytoplasm, Ligase, Nucleotide-binding, Phosphoprotein, Polymorphism, Protein biosynthesis
Deposited on 2007-12-04, released 2008-02-05
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.31 Å
R-factor: 0.197
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: lysyl-tRNA synthetase
    Species: Homo sapiens [TaxId:9606]
    Gene: KARS, KIAA0070
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3bjua1, d3bjua2
  • Chain 'B':
    Compound: lysyl-tRNA synthetase
    Species: Homo sapiens [TaxId:9606]
    Gene: KARS, KIAA0070
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3bjub1, d3bjub2
  • Chain 'C':
    Compound: lysyl-tRNA synthetase
    Species: Homo sapiens [TaxId:9606]
    Gene: KARS, KIAA0070
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3bjuc1, d3bjuc2
  • Chain 'D':
    Compound: lysyl-tRNA synthetase
    Species: Homo sapiens [TaxId:9606]
    Gene: KARS, KIAA0070
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3bjud1, d3bjud2
  • Heterogens: CA, LYS, ATP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3bjuA (A:)
msvdpnqyykirsqaihqlkvngedpyphkfhvdisltdfiqkyshlqpgdhltditlkv
agrihakrasggklifydlrgegvklqvmansrnykseeefihinnklrrgdiigvqgnp
gktkkgelsiipyeitllspclhmlphlhfglkdketryrqryldlilndfvrqkfiirs
kiityirsfldelgfleietpmmniipggavakpfityhneldmnlymriapelyhkmlv
vggidrvyeigrqfrnegidlthnpefttcefymayadyhdlmeitekmvsgmvkhitgs
ykvtyhpdgpegqaydvdftppfrrinmveelekalgmklpetnlfeteetrkilddicv
akavecppprttarlldklvgeflevtcinptficdhpqimsplakwhrskeglterfel
fvmkkeicnaytelndpmrqrqlfeeqakakaagddeamfidenfctaleyglpptagwg
mgidrvamfltdsnnikevllfpamkpedkkenlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3bjuA (A:)
svdpnqyykirsqaihqlkvngedpyphkfhvdisltdfiqkyshlqpgdhltditlkva
grihakrasggklifydlrgegvklqvmansrnykseeefihinnklrrgdiigvqgnpg
ktkkgelsiipyeitllspclhmlphlkdketryrqryldlilndfvrqkfiirskiity
irsfldelgfleietpmmniipggavakpfityhneldmnlymriapelyhkmlvvggid
rvyeigrqfrnegidlthnpefttcefymayadyhdlmeitekmvsgmvkhitgsykvty
hpdgpegqaydvdftppfrrinmveelekalgmklpetnlfeteetrkilddicvakave
cppprttarlldklvgeflevtcinptficdhpqimsplakwhrskeglterfelfvmkk
eicnaytelndpmrqrqlfeeqakakaagddeamfidenfctaleyglpptagwgmgidr
vamfltdsnnikevllfpamkpe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3bjuB (B:)
msvdpnqyykirsqaihqlkvngedpyphkfhvdisltdfiqkyshlqpgdhltditlkv
agrihakrasggklifydlrgegvklqvmansrnykseeefihinnklrrgdiigvqgnp
gktkkgelsiipyeitllspclhmlphlhfglkdketryrqryldlilndfvrqkfiirs
kiityirsfldelgfleietpmmniipggavakpfityhneldmnlymriapelyhkmlv
vggidrvyeigrqfrnegidlthnpefttcefymayadyhdlmeitekmvsgmvkhitgs
ykvtyhpdgpegqaydvdftppfrrinmveelekalgmklpetnlfeteetrkilddicv
akavecppprttarlldklvgeflevtcinptficdhpqimsplakwhrskeglterfel
fvmkkeicnaytelndpmrqrqlfeeqakakaagddeamfidenfctaleyglpptagwg
mgidrvamfltdsnnikevllfpamkpedkkenlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3bjuB (B:)
dpnqyykirsqaihqlkvngedpyphkfhvdisltdfiqkyshlqpgdhltditlkvagr
ihakrasggklifydlrgegvklqvmansrnykseeefihinnklrrgdiigvqgnpgkt
kkgelsiipyeitllspclhmlpketryrqryldlilndfvrqkfiirskiityirsfld
elgfleietpmmniipggavakpfityhneldmnlymriapelyhkmlvvggidrvyeig
rqfrnegidlthnpefttcefymayadyhdlmeitekmvsgmvkhitgsykvtyhpdgpe
gqaydvdftppfrrinmveelekalgmklpetnlfeteetrkilddicvakavecppprt
tarlldklvgeflevtcinptficdhpqimsplakwhrskeglterfelfvmkkeicnay
telndpmrqrqlfeeqakakaagddeamfidenfctaleyglpptagwgmgidrvamflt
dsnnikevllfpamk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3bjuC (C:)
msvdpnqyykirsqaihqlkvngedpyphkfhvdisltdfiqkyshlqpgdhltditlkv
agrihakrasggklifydlrgegvklqvmansrnykseeefihinnklrrgdiigvqgnp
gktkkgelsiipyeitllspclhmlphlhfglkdketryrqryldlilndfvrqkfiirs
kiityirsfldelgfleietpmmniipggavakpfityhneldmnlymriapelyhkmlv
vggidrvyeigrqfrnegidlthnpefttcefymayadyhdlmeitekmvsgmvkhitgs
ykvtyhpdgpegqaydvdftppfrrinmveelekalgmklpetnlfeteetrkilddicv
akavecppprttarlldklvgeflevtcinptficdhpqimsplakwhrskeglterfel
fvmkkeicnaytelndpmrqrqlfeeqakakaagddeamfidenfctaleyglpptagwg
mgidrvamfltdsnnikevllfpamkpedkkenlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3bjuC (C:)
dpnqyykirsqaihqlkvngedpyphkfhvdisltdfiqkyshlqpgdhltditlkvagr
ihakrasggklifydlrgegvklqvmansrnykseeefihinnklrrgdiigvqgnpgkt
kkgelsiipyeitllspclhmlphglkdketryrqryldlilndfvrqkfiirskiityi
rsfldelgfleietpmmniipggavakpfityhneldmnlymriapelyhkmlvvggidr
vyeigrqfrnegidlthnpefttcefymayadyhdlmeitekmvsgmvkhitgsykvtyh
pdgpegqaydvdftppfrrinmveelekalgmklpetnlfeteetrkilddicvakavec
ppprttarlldklvgeflevtcinptficdhpqimsplakwhrskeglterfelfvmkke
icnaytelndpmrqrqlfeeqakakaagddeamfidenfctaleyglpptagwgmgidrv
amfltdsnnikevllfpamkp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3bjuD (D:)
msvdpnqyykirsqaihqlkvngedpyphkfhvdisltdfiqkyshlqpgdhltditlkv
agrihakrasggklifydlrgegvklqvmansrnykseeefihinnklrrgdiigvqgnp
gktkkgelsiipyeitllspclhmlphlhfglkdketryrqryldlilndfvrqkfiirs
kiityirsfldelgfleietpmmniipggavakpfityhneldmnlymriapelyhkmlv
vggidrvyeigrqfrnegidlthnpefttcefymayadyhdlmeitekmvsgmvkhitgs
ykvtyhpdgpegqaydvdftppfrrinmveelekalgmklpetnlfeteetrkilddicv
akavecppprttarlldklvgeflevtcinptficdhpqimsplakwhrskeglterfel
fvmkkeicnaytelndpmrqrqlfeeqakakaagddeamfidenfctaleyglpptagwg
mgidrvamfltdsnnikevllfpamkpedkkenlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3bjuD (D:)
vdpnqyykirsqaihqlkvngedpyphkfhvdisltdfiqkyshlqpgdhltditlkvag
rihakrasggklifydlrgegvklqvmansrnykseeefihinnklrrgdiigvqgnpgk
tkkgelsiipyeitllspclhmlpkdketryrqryldlilndfvrqkfiirskiityirs
fldelgfleietpmmniipggavakpfityhneldmnlymriapelyhkmlvvggidrvy
eigrqfrnegidlthnpefttcefymayadyhdlmeitekmvsgmvkhitgsykvtyhpd
gpegqaydvdftppfrrinmveelekalgmklpetnlfeteetrkilddicvakavecpp
prttarlldklvgeflevtcinptficdhpqimsplakwhrskeglterfelfvmkkeic
naytelndpmrqrqlfeeqakakaagddeamfidenfctaleyglpptagwgmgidrvam
fltdsnnikevllfpamkp