PDB entry 3bjt

View 3bjt on RCSB PDB site
Description: Pyruvate kinase M2 is a phosphotyrosine binding protein
Deposited on 2007-12-04, released 2008-03-04
The last revision was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.211
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pyruvate kinase isozymes M1/M2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14618 (Start-529)
      • conflict (377)
  • Chain 'B':
    Compound: Pyruvate kinase isozymes M1/M2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14618 (Start-529)
      • conflict (377)
  • Chain 'C':
    Compound: Pyruvate kinase isozymes M1/M2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14618 (Start-529)
      • conflict (377)
  • Chain 'D':
    Compound: Pyruvate kinase isozymes M1/M2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14618 (Start-529)
      • conflict (377)
  • Heterogens: OXL, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3bjtA (A:)
skphseagtafiqtqqlhaamadtflehmcrldidsppitarntgiictigpasrsvetl
kemiksgmnvarlnfshgtheyhaetiknvrtatesfasdpilyrpvavaldtkgpeirt
glikgsgtaevelkkgatlkitldnaymekcdenilwldyknickvvevgskiyvddgli
slqvkqkgadflvtevenggslgskkgvnlpgaavdlpavsekdiqdlkfgveqdvdmvf
asfirkasdvhevrkvlgekgknikiiskienhegvrrfdeileasdgimvargdlgiei
paekvflaqkmmigrcnragkpvicatqmlesmikkprptraegsdvanavldgadciml
sgetakgdypleavrmqnliareaeaaiyhlqlfeelrrlapitsdpteatavgaveasf
kccsgaiivltksgrsahqvaryrprapiiavtrnpqtarqahlyrgifpvlckdpvqea
waedvdlrvnfamnvgkargffkkgdvvivltgwrpgsgftntmrvvpvp

    Sequence, based on observed residues (ATOM records):
    >3bjtA (A:)
qtqqlhaamadtflehmcrldidsppitarntgiictigpasrsvetlkemiksgmnvar
lnfshgtheyhaetiknvrtatesfasdpilyrpvavaldtkgpeirtglikgsgtaeve
lkkgatlkitldnaymekcdenilwldyknickvvevgskiyvddglislqvkqkgadfl
vtevenggslgskkgvnlpgaavdlpavsekdiqdlkfgveqdvdmvfasfirkasdvhe
vrkvlgekgknikiiskienhegvrrfdeileasdgimvargdlgieipaekvflaqkmm
igrcnragkpvicatqmlesmikkprptraegsdvanavldgadcimlsgetakgdyple
avrmqnliareaeaaiyhlqlfeelrrlapitsdpteatavgaveasfkccsgaiivltk
sgrsahqvaryrprapiiavtrnpqtarqahlyrgifpvlckdpvqeawaedvdlrvnfa
mnvgkargffkkgdvvivltgftntmrvvpvp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3bjtB (B:)
skphseagtafiqtqqlhaamadtflehmcrldidsppitarntgiictigpasrsvetl
kemiksgmnvarlnfshgtheyhaetiknvrtatesfasdpilyrpvavaldtkgpeirt
glikgsgtaevelkkgatlkitldnaymekcdenilwldyknickvvevgskiyvddgli
slqvkqkgadflvtevenggslgskkgvnlpgaavdlpavsekdiqdlkfgveqdvdmvf
asfirkasdvhevrkvlgekgknikiiskienhegvrrfdeileasdgimvargdlgiei
paekvflaqkmmigrcnragkpvicatqmlesmikkprptraegsdvanavldgadciml
sgetakgdypleavrmqnliareaeaaiyhlqlfeelrrlapitsdpteatavgaveasf
kccsgaiivltksgrsahqvaryrprapiiavtrnpqtarqahlyrgifpvlckdpvqea
waedvdlrvnfamnvgkargffkkgdvvivltgwrpgsgftntmrvvpvp

    Sequence, based on observed residues (ATOM records):
    >3bjtB (B:)
qtqqlhaamadtflehmcrldidsppitarntgiictigpasrsvetlkemiksgmnvar
lnfshgtheyhaetiknvrtatesfasdpilyrpvavaldtkgpeirtglikgsgtaeve
lkkgatlkitldnaymekcdenilwldyknickvvevgskiyvddglislqvkqkgadfl
vtevenggslgskkgvnlpgaavdlpavsekdiqdlkfgveqdvdmvfasfirkasdvhe
vrkvlgekgknikiiskienhegvrrfdeileasdgimvargdlgieipaekvflaqkmm
igrcnragkpvicatqmlesmikkprptraegsdvanavldgadcimlsgetakgdyple
avrmqnliareaeaaiyhlqlfeelrrlapitsdpteatavgaveasfkccsgaiivltk
sgrsahqvaryrprapiiavtrnpqtarqahlyrgifpvlckdpvqeawaedvdlrvnfa
mnvgkargffkkgdvvivltgftntmrvvpvp

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3bjtC (C:)
skphseagtafiqtqqlhaamadtflehmcrldidsppitarntgiictigpasrsvetl
kemiksgmnvarlnfshgtheyhaetiknvrtatesfasdpilyrpvavaldtkgpeirt
glikgsgtaevelkkgatlkitldnaymekcdenilwldyknickvvevgskiyvddgli
slqvkqkgadflvtevenggslgskkgvnlpgaavdlpavsekdiqdlkfgveqdvdmvf
asfirkasdvhevrkvlgekgknikiiskienhegvrrfdeileasdgimvargdlgiei
paekvflaqkmmigrcnragkpvicatqmlesmikkprptraegsdvanavldgadciml
sgetakgdypleavrmqnliareaeaaiyhlqlfeelrrlapitsdpteatavgaveasf
kccsgaiivltksgrsahqvaryrprapiiavtrnpqtarqahlyrgifpvlckdpvqea
waedvdlrvnfamnvgkargffkkgdvvivltgwrpgsgftntmrvvpvp

    Sequence, based on observed residues (ATOM records):
    >3bjtC (C:)
qtqqlhaamadtflehmcrldidsppitarntgiictigpasrsvetlkemiksgmnvar
lnfshgtheyhaetiknvrtatesfasdpilyrpvavaldtkgpeirtglikgsgtaeve
lkkgatlkitldnaymekcdenilwldyknickvvevgskiyvddglislqvkqkgadfl
vtevenggslgskkgvnlpgaavdlpavsekdiqdlkfgveqdvdmvfasfirkasdvhe
vrkvlgekgknikiiskienhegvrrfdeileasdgimvargdlgieipaekvflaqkmm
igrcnragkpvicatqmlesmikkprptraegsdvanavldgadcimlsgetakgdyple
avrmqnliareaeaaiyhlqlfeelrrlapitsdpteatavgaveasfkccsgaiivltk
sgrsahqvaryrprapiiavtrnpqtarqahlyrgifpvlckdpvqeawaedvdlrvnfa
mnvgkargffkkgdvvivltgftntmrvvpvp

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3bjtD (D:)
skphseagtafiqtqqlhaamadtflehmcrldidsppitarntgiictigpasrsvetl
kemiksgmnvarlnfshgtheyhaetiknvrtatesfasdpilyrpvavaldtkgpeirt
glikgsgtaevelkkgatlkitldnaymekcdenilwldyknickvvevgskiyvddgli
slqvkqkgadflvtevenggslgskkgvnlpgaavdlpavsekdiqdlkfgveqdvdmvf
asfirkasdvhevrkvlgekgknikiiskienhegvrrfdeileasdgimvargdlgiei
paekvflaqkmmigrcnragkpvicatqmlesmikkprptraegsdvanavldgadciml
sgetakgdypleavrmqnliareaeaaiyhlqlfeelrrlapitsdpteatavgaveasf
kccsgaiivltksgrsahqvaryrprapiiavtrnpqtarqahlyrgifpvlckdpvqea
waedvdlrvnfamnvgkargffkkgdvvivltgwrpgsgftntmrvvpvp

    Sequence, based on observed residues (ATOM records):
    >3bjtD (D:)
qtqqlhaamadtflehmcrldidsppitarntgiictigpasrsvetlkemiksgmnvar
lnfshgtheyhaetiknvrtatesfasdpilyrpvavaldtkgpeirtglikgsgtaeve
lkkgatlkitldnaymekcdenilwldyknickvvevgskiyvddglislqvkqkgadfl
vtevenggslgskkgvnlpgaavdlpavsekdiqdlkfgveqdvdmvfasfirkasdvhe
vrkvlgekgknikiiskienhegvrrfdeileasdgimvargdlgieipaekvflaqkmm
igrcnragkpvicatqmlesmikkprptraegsdvanavldgadcimlsgetakgdyple
avrmqnliareaeaaiyhlqlfeelrrlapitsdpteatavgaveasfkccsgaiivltk
sgrsahqvaryrprapiiavtrnpqtarqahlyrgifpvlckdpvqeawaedvdlrvnfa
mnvgkargffkkgdvvivltgftntmrvvpvp