PDB entry 3biy

View 3biy on RCSB PDB site
Description: Crystal structure of p300 histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA
Class: transferase
Keywords: p300 HAT, Bisubstrate inhibitor, protein-inhibitor complex, TRANSFERASE
Deposited on 2007-12-02, released 2008-02-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone acetyltransferase p300
    Species: Homo sapiens [TaxId:9606]
    Gene: EP300, P300
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q09472 (0-End)
      • engineered (350)
      • engineered (365)
    Domains in SCOPe 2.08: d3biya_
  • Heterogens: BR, 01K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3biyA (A:)
kfsakrlpstrlgtflenrvndflrrqnhpesgevtvrvvhasdktvevkpgmkarfvds
gemaesfpyrtkalfafeeidgvdlcffgmhvqeygsdcpppnqrrvyisyldsvhffrp
kclrtavyheiligyleyvkklgyttghiwacppsegddyifhchppdqkipkpkrlqew
ykkmldkavserivhdykdifkqatedrltsakelpyfegdfwpnvleesikeleqeeee
rkreentsnestdvtkgdsknakkknnkktsknksslsrgnkkkpgmpnvsndlsqklya
tmekhkevffvirliagpaanslppivdpdplipcdlmdgrdafltlardrhlefsslrr
aqwstgcmlvelhtqsqdrf

    Sequence, based on observed residues (ATOM records): (download) 
    >3biyA (A:)
kfsakrlpstrlgtflenrvndflrrqnhpesgevtvrvvhasdktvevkpgmkarfvds
gemaesfpyrtkalfafeeidgvdlcffgmhvqeygsdcpppnqrrvyisyldsvhffrp
kclrtavyheiligyleyvkklgyttghiwacppsegddyifhchppdqkipkpkrlqew
ykkmldkavserivhdykdifkqatedrltsakelpyfegdfwpnvleesikesqklyat
mekhkevffvirliagpaanslppivdpdplipcdlmdgrdafltlardrhlefsslrra
qwstgcmlvelhtqsqd