PDB entry 3bhh

View 3bhh on RCSB PDB site
Description: Crystal structure of human calcium/calmodulin-dependent protein kinase IIB isoform 1 (CAMK2B)
Class: transferase
Keywords: CAMK2B, CAM2, CAMK2, CaM kinase II beta chain, CAMK II beta subunit, Calcium/calmodulion dependent protein kinase II beta, EC:2.7.1.123, MGC29528, Proline rich calmodulin dependent protein kinase, Structural Genomics Consortium, SGC, ATP-binding, Calmodulin-binding, Nucleotide-binding, Phosphoprotein, Serine/threonine-protein kinase, Transferase
Deposited on 2007-11-28, released 2007-12-11
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.225
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Calcium/calmodulin-dependent protein kinase type II beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: CAMK2B, CAM2, CAMKB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13554 (2-End)
      • expression tag (0-1)
    Domains in SCOPe 2.05: d3bhha_
  • Chain 'B':
    Compound: Calcium/calmodulin-dependent protein kinase type II beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: CAMK2B, CAM2, CAMKB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13554 (2-End)
      • expression tag (1)
    Domains in SCOPe 2.05: d3bhhb_
  • Chain 'C':
    Compound: Calcium/calmodulin-dependent protein kinase type II beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: CAMK2B, CAM2, CAMKB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13554 (2-End)
      • expression tag (1)
    Domains in SCOPe 2.05: d3bhhc_
  • Chain 'D':
    Compound: Calcium/calmodulin-dependent protein kinase type II beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: CAMK2B, CAM2, CAMKB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13554 (2-End)
      • expression tag (1)
    Domains in SCOPe 2.05: d3bhhd_
  • Heterogens: 5CP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3bhhA (A:)
    smtdeyqlyedigkgafsvvrrcvklctgheyaakiintkklsardhqklerearicrll
    khsnivrlhdsiseegfhylvfdlvtggelfedivareyyseadashciqqileavlhch
    qmgvvhrdlkpenlllaskckgaavkladfglaievqgdqqawfgfagtpgylspevlrk
    eaygkpvdiwacgvilyillvgyppfwdedqhklyqqikagaydfpspewdtvtpeaknl
    inqmltinpakritahealkhpwvcqrstvasmmhrqetveclkkfnarrklkga
    

    Sequence, based on observed residues (ATOM records): (download)
    >3bhhA (A:)
    smtdeyqlyedigsvvrrcvklctgheyaakiintkklsardhqklerearicrllkhsn
    ivrlhdsiseegfhylvfdlvtggelfedivareyyseadashciqqileavlhchqmgv
    vhrdlkpenlllaskckgaavkladfglaievqgdqqawfgfagtpgylspevlrkeayg
    kpvdiwacgvilyillvgyppfwdedqhklyqqikagaydfpspewdtvtpeaknlinqm
    ltinpakritahealkhpwvcqrstvasmmhrqetveclkkfnarrklk
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3bhhB (B:)
    smtdeyqlyedigkgafsvvrrcvklctgheyaakiintkklsardhqklerearicrll
    khsnivrlhdsiseegfhylvfdlvtggelfedivareyyseadashciqqileavlhch
    qmgvvhrdlkpenlllaskckgaavkladfglaievqgdqqawfgfagtpgylspevlrk
    eaygkpvdiwacgvilyillvgyppfwdedqhklyqqikagaydfpspewdtvtpeaknl
    inqmltinpakritahealkhpwvcqrstvasmmhrqetveclkkfnarrklkga
    

    Sequence, based on observed residues (ATOM records): (download)
    >3bhhB (B:)
    mtdeyqlyedigksvvrrcvklctgheyaakiintkklsardhqklerearicrllkhsn
    ivrlhdsiseegfhylvfdlvtggelfedivareyyseadashciqqileavlhchqmgv
    vhrdlkpenlllaskckgaavkladfglaievqgdqqawfgfagtpgylspevlrkeayg
    kpvdiwacgvilyillvgyppfwdedqhklyqqikagaydfpspewdtvtpeaknlinqm
    ltinpakritahealkhpwvcqrstvasmmhrqetveclkkfnarrklk
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >3bhhC (C:)
    smtdeyqlyedigkgafsvvrrcvklctgheyaakiintkklsardhqklerearicrll
    khsnivrlhdsiseegfhylvfdlvtggelfedivareyyseadashciqqileavlhch
    qmgvvhrdlkpenlllaskckgaavkladfglaievqgdqqawfgfagtpgylspevlrk
    eaygkpvdiwacgvilyillvgyppfwdedqhklyqqikagaydfpspewdtvtpeaknl
    inqmltinpakritahealkhpwvcqrstvasmmhrqetveclkkfnarrklkga
    

    Sequence, based on observed residues (ATOM records): (download)
    >3bhhC (C:)
    mtdeyqlyedivvrrcvklctgheyaakiintkklsardhqklerearicrllkhsnivr
    lhdsiseegfhylvfdlvtggelfedivareyyseadashciqqileavlhchqmgvvhr
    dlkpenlllaskckgaavkladfglaievqgdqqawfgfagtpgylspevlrkeaygkpv
    diwacgvilyillvgyppfwdedqhklyqqikagaydfpspewdtvtpeaknlinqmlti
    npakritahealkhpwvcqrstvasmmhrqetveclkkfnarrkl
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >3bhhD (D:)
    smtdeyqlyedigkgafsvvrrcvklctgheyaakiintkklsardhqklerearicrll
    khsnivrlhdsiseegfhylvfdlvtggelfedivareyyseadashciqqileavlhch
    qmgvvhrdlkpenlllaskckgaavkladfglaievqgdqqawfgfagtpgylspevlrk
    eaygkpvdiwacgvilyillvgyppfwdedqhklyqqikagaydfpspewdtvtpeaknl
    inqmltinpakritahealkhpwvcqrstvasmmhrqetveclkkfnarrklkga
    

    Sequence, based on observed residues (ATOM records): (download)
    >3bhhD (D:)
    mtdeyqlyedivvrrcvklctgheyaakiintkklsardhqklerearicrllkhsnivr
    lhdsiseegfhylvfdlvtggelfedivareyyseadashciqqileavlhchqmgvvhr
    dlkpenlllaskckgaavkladfglaievqgdqqawfgfagtpgylspevlrkeaygkpv
    diwacgvilyillvgyppfwdedqhklyqqikagaydfpspewdtvtpeaknlinqmlti
    npakritahealkhpwvcqrstvasmmhrqetveclkkfnarrklk