PDB entry 3bg9

View 3bg9 on RCSB PDB site
Description: crystal structure of human pyruvate carboxylase (missing the biotin carboxylase domain at the n-terminus) f1077a mutant
Deposited on 2007-11-26, released 2008-02-26
The last revision was dated 2021-10-20, with a file datestamp of 2021-10-15.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pyruvate carboxylase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: PC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11498 (21-717)
      • expression tag (0-20)
      • engineered mutation (616)
  • Chain 'B':
    Compound: Pyruvate carboxylase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: PC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11498 (21-717)
      • expression tag (0-20)
      • engineered mutation (616)
  • Chain 'C':
    Compound: Pyruvate carboxylase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: PC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11498 (21-717)
      • expression tag (0-20)
      • engineered mutation (616)
  • Chain 'D':
    Compound: Pyruvate carboxylase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: PC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11498 (21-717)
      • expression tag (0-20)
      • engineered mutation (616)
  • Heterogens: MN

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3bg9A (A:)
mgsshhhhhhssglvprgshmdenpelfqlrpaqnraqkllhylghvmvngpttpipvka
spsptdpvvpavpigpppagfrdillregpegfaravrnhpglllmdttfrdahqsllat
rvrthdlkkiapyvahnfsklfsmenwggatfdvamrflyecpwrrlqelrelipnipfq
mllrganavgytnypdnvvfkfcevakengmdvfrvfdslnylpnmllgmeaagsaggvv
eaaisytgdvadpsrtkyslqyymglaeelvragthilcikdmagllkptactmlvsslr
drfpdlplhihthdtsgagvaamlacaqagadvvdvaadsmsgmtsqpsmgalvactrgt
pldtevpmervfdyseywegarglyaafdctatmksgnsdvyeneipggqytnlhfqahs
mglgskfkevkkayveanqmlgdlikvtpsskivgdlaqfmvqnglsraeaeaqaeelsf
prsvveflqgyigvphggfpepfrskvlkdlprvegrpgaslppldlqalekelvdrhge
evtpedvlsaamypdvfahfkdftatfgpldslntrlflqgpkiaeefevelergktlhi
kalavsdlnragqrqvafelngqlrsilvkdtqamkemhfhpkalkdvkgqigapmpgkv
idikvvagakvakgqplcvlsamkmetvvtspmegtvrkvhvtkdmtlegddlileie

    Sequence, based on observed residues (ATOM records):
    >3bg9A (A:)
qnraqkllhylghvmvngpttpipvkaspsptdpvvpavpigpppagfrdillregpegf
aravrnhpglllmdttfrdahqsllatrvrthdlkkiapyvahnfsklfsmenwggatfd
vamrflyecpwrrlqelrelipnipfqmllrganavgytnypdnvvfkfcevakengmdv
frvfdslnylpnmllgmeaagsaggvveaaisytgdvadpsrtkyslqyymglaeelvra
gthilcikdmagllkptactmlvsslrdrfpdlplhihthdtsgagvaamlacaqagadv
vdvaadsmsgmtsqpsmgalvactrgtpldtevpmervfdyseywegarglyaafdctat
mksgnsdvyeneipggqytnlhfqahsmglgskfkevkkayveanqmlgdlikvtpsski
vgdlaqfmvqnglsraeaeaqaeelsfprsvveflqgyigvphggfpepfrskvlkdlpr
vegrpgaslppldlqalekelvdrhgeevtpedvlsaamypdvfahfkdftatfgpldsl
ntrlflqgpkiaeefevelergktlhikalavsdlnragqrqvafelngqlrsilvkdtq
a

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3bg9B (B:)
mgsshhhhhhssglvprgshmdenpelfqlrpaqnraqkllhylghvmvngpttpipvka
spsptdpvvpavpigpppagfrdillregpegfaravrnhpglllmdttfrdahqsllat
rvrthdlkkiapyvahnfsklfsmenwggatfdvamrflyecpwrrlqelrelipnipfq
mllrganavgytnypdnvvfkfcevakengmdvfrvfdslnylpnmllgmeaagsaggvv
eaaisytgdvadpsrtkyslqyymglaeelvragthilcikdmagllkptactmlvsslr
drfpdlplhihthdtsgagvaamlacaqagadvvdvaadsmsgmtsqpsmgalvactrgt
pldtevpmervfdyseywegarglyaafdctatmksgnsdvyeneipggqytnlhfqahs
mglgskfkevkkayveanqmlgdlikvtpsskivgdlaqfmvqnglsraeaeaqaeelsf
prsvveflqgyigvphggfpepfrskvlkdlprvegrpgaslppldlqalekelvdrhge
evtpedvlsaamypdvfahfkdftatfgpldslntrlflqgpkiaeefevelergktlhi
kalavsdlnragqrqvafelngqlrsilvkdtqamkemhfhpkalkdvkgqigapmpgkv
idikvvagakvakgqplcvlsamkmetvvtspmegtvrkvhvtkdmtlegddlileie

    Sequence, based on observed residues (ATOM records):
    >3bg9B (B:)
qnraqkllhylghvmvngpttpipvkaspsptdpvvpavpigpppagfrdillregpegf
aravrnhpglllmdttfrdahqsllatrvrthdlkkiapyvahnfsklfsmenwggatfd
vamrflyecpwrrlqelrelipnipfqmllrganavgytnypdnvvfkfcevakengmdv
frvfdslnylpnmllgmeaagsaggvveaaisytgdvadpsrtkyslqyymglaeelvra
gthilcikdmagllkptactmlvsslrdrfpdlplhihthdtsgagvaamlacaqagadv
vdvaadsmsgmtsqpsmgalvactrgtpldtevpmervfdyseywegarglyaafdctat
mksgnsdvyeneipggqytnlhfqahsmglgskfkevkkayveanqmlgdlikvtpsski
vgdlaqfmvqnglsraeaeaqaeelsfprsvveflqgyigvphggfpepfrskvlkdlpr
vegrpgaslppldlqalekelvdrhgeevtpedvlsaamypdvfahfkdftatfgpldsl
ntrlflqgpkiaeefevelergktlhikalavsdlnragqrqvafelngqlrsilvkdtq
a

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3bg9C (C:)
mgsshhhhhhssglvprgshmdenpelfqlrpaqnraqkllhylghvmvngpttpipvka
spsptdpvvpavpigpppagfrdillregpegfaravrnhpglllmdttfrdahqsllat
rvrthdlkkiapyvahnfsklfsmenwggatfdvamrflyecpwrrlqelrelipnipfq
mllrganavgytnypdnvvfkfcevakengmdvfrvfdslnylpnmllgmeaagsaggvv
eaaisytgdvadpsrtkyslqyymglaeelvragthilcikdmagllkptactmlvsslr
drfpdlplhihthdtsgagvaamlacaqagadvvdvaadsmsgmtsqpsmgalvactrgt
pldtevpmervfdyseywegarglyaafdctatmksgnsdvyeneipggqytnlhfqahs
mglgskfkevkkayveanqmlgdlikvtpsskivgdlaqfmvqnglsraeaeaqaeelsf
prsvveflqgyigvphggfpepfrskvlkdlprvegrpgaslppldlqalekelvdrhge
evtpedvlsaamypdvfahfkdftatfgpldslntrlflqgpkiaeefevelergktlhi
kalavsdlnragqrqvafelngqlrsilvkdtqamkemhfhpkalkdvkgqigapmpgkv
idikvvagakvakgqplcvlsamkmetvvtspmegtvrkvhvtkdmtlegddlileie

    Sequence, based on observed residues (ATOM records):
    >3bg9C (C:)
qnraqkllhylghvmvngpttpipvkaspsptdpvvpavpigpppagfrdillregpegf
aravrnhpglllmdttfrdahqsllatrvrthdlkkiapyvahnfsklfsmenwggatfd
vamrflyecpwrrlqelrelipnipfqmllrganavgytnypdnvvfkfcevakengmdv
frvfdslnylpnmllgmeaagsaggvveaaisytgdvadpsrtkyslqyymglaeelvra
gthilcikdmagllkptactmlvsslrdrfpdlplhihthdtsgagvaamlacaqagadv
vdvaadsmsgmtsqpsmgalvactrgtpldtevpmervfdyseywegarglyaafdctat
mksgnsdvyeneipggqytnlhfqahsmglgskfkevkkayveanqmlgdlikvtpsski
vgdlaqfmvqnglsraeaeaqaeelsfprsvveflqgyigvphggfpepfrskvlkdlpr
vegrpgaslppldlqalekelvdrhgeevtpedvlsaamypdvfahfkdftatfgpldsl
ntrlflqgpkiaeefevelergktlhikalavsdlnragqrqvafelngqlrsilvkdtq
a

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3bg9D (D:)
mgsshhhhhhssglvprgshmdenpelfqlrpaqnraqkllhylghvmvngpttpipvka
spsptdpvvpavpigpppagfrdillregpegfaravrnhpglllmdttfrdahqsllat
rvrthdlkkiapyvahnfsklfsmenwggatfdvamrflyecpwrrlqelrelipnipfq
mllrganavgytnypdnvvfkfcevakengmdvfrvfdslnylpnmllgmeaagsaggvv
eaaisytgdvadpsrtkyslqyymglaeelvragthilcikdmagllkptactmlvsslr
drfpdlplhihthdtsgagvaamlacaqagadvvdvaadsmsgmtsqpsmgalvactrgt
pldtevpmervfdyseywegarglyaafdctatmksgnsdvyeneipggqytnlhfqahs
mglgskfkevkkayveanqmlgdlikvtpsskivgdlaqfmvqnglsraeaeaqaeelsf
prsvveflqgyigvphggfpepfrskvlkdlprvegrpgaslppldlqalekelvdrhge
evtpedvlsaamypdvfahfkdftatfgpldslntrlflqgpkiaeefevelergktlhi
kalavsdlnragqrqvafelngqlrsilvkdtqamkemhfhpkalkdvkgqigapmpgkv
idikvvagakvakgqplcvlsamkmetvvtspmegtvrkvhvtkdmtlegddlileie

    Sequence, based on observed residues (ATOM records):
    >3bg9D (D:)
qnraqkllhylghvmvngpttpipvkaspsptdpvvpavpigpppagfrdillregpegf
aravrnhpglllmdttfrdahqsllatrvrthdlkkiapyvahnfsklfsmenwggatfd
vamrflyecpwrrlqelrelipnipfqmllrganavgytnypdnvvfkfcevakengmdv
frvfdslnylpnmllgmeaagsaggvveaaisytgdvadpsrtkyslqyymglaeelvra
gthilcikdmagllkptactmlvsslrdrfpdlplhihthdtsgagvaamlacaqagadv
vdvaadsmsgmtsqpsmgalvactrgtpldtevpmervfdyseywegarglyaafdctat
mksgnsdvyeneipggqytnlhfqahsmglgskfkevkkayveanqmlgdlikvtpsski
vgdlaqfmvqnglsraeaeaqaeelsfprsvveflqgyigvphggfpepfrskvlkdlpr
vegrpgaslppldlqalekelvdrhgeevtpedvlsaamypdvfahfkdftatfgpldsl
ntrlflqgpkiaeefevelergktlhikalavsdlnragqrqvafelngqlrsilvkdtq
a