PDB entry 3be1

View 3be1 on RCSB PDB site
Description: Dual specific bH1 Fab in complex with the extracellular domain of HER2/ErbB-2
Class: transferase
Keywords: Fab Complex, ATP-binding, Glycoprotein, Kinase, Membrane, Nucleotide-binding, Phosphorylation, Receptor, Transferase, Transmembrane, Tyrosine-protein kinase
Deposited on 2007-11-15, released 2008-11-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Receptor tyrosine-protein kinase erbB-2
    Species: Homo sapiens [TaxId:9606]
    Gene: ERBB2, HER2, NEU, NGL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3be1a1, d3be1a2, d3be1a3, d3be1a4
  • Chain 'H':
    Compound: Fab Fragment-Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3BDY
    Domains in SCOPe 2.08: d3be1h_
  • Chain 'L':
    Compound: Fab Fragment-Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3BDY (0-End)
    Domains in SCOPe 2.08: d3be1l1, d3be1l2
  • Heterogens: NAG, MES

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3be1A (A:)
tqvctgtdmklrlpaspethldmlrhlyqgcqvvqgnleltylptnaslsflqdiqevqg
yvliahnqvrqvplqrlrivrgtqlfednyalavldngdplnnttpvtgaspgglrelql
rslteilkggvliqrnpqlcyqdtilwkdifhknnqlaltlidtnrsrachpcspmckgs
rcwgessedcqsltrtvcaggcarckgplptdccheqcaagctgpkhsdclaclhfnhsg
icelhcpalvtyntdtfesmpnpegrytfgascvtacpynylstdvgsctlvcplhnqev
taedgtqrcekcskpcarvcyglgmehlrevravtsaniqefagckkifgslaflpesfd
gdpasntaplqpeqlqvfetleeitgylyisawpdslpdlsvfqnlqvirgrilhngays
ltlqglgiswlglrslrelgsglalihhnthlcfvhtvpwdqlfrnphqallhtanrped
ecvgeglachqlcarghcwgpgptqcvncsqflrgqecveecrvlqglpreyvnarhclp
chpecqpqngsvtcfgpeadqcvacahykdppfcvarcpsgvkpdlsympiwkfpdeega
cqpcpincthscvdlddkgcpaeq

    Sequence, based on observed residues (ATOM records): (download) 
    >3be1A (A:)
tqvctgtdmklrlpaspethldmlrhlyqgcqvvqgnleltylptnaslsflqdiqevqg
yvliahnqvrqvplqrlrivrgtqlfednyalavldngdpspgglrelqlrslteilkgg
vliqrnpqlcyqdtilwkdifhknnqlaltlidtnrsrachpcspmckgsrcwgessedc
qsltrtvcaggcarckgplptdccheqcaagctgpkhsdclaclhfnhsgicelhcpalv
tyntdtfesmpnpegrytfgascvtacpynylstdvgsctlvcplhnqevtaedgtqrce
kcskpcarvcyglgmehlrevravtsaniqefagckkifgslaflpesfdgntaplqpeq
lqvfetleeitgylyisawpdslpdlsvfqnlqvirgrilhngaysltlqglgiswlglr
slrelgsglalihhnthlcfvhtvpwdqlfrnphqallhtanrpedecvgeglachqlca
rghcwgpgptqcvncsqflrgqecveecrvlqglpreyvnarhclpchpecqpqngsvtc
fgpeadqcvacahykdppfcvarcpsiwkfpdeegacqpcpin

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >3be1H (H:)
eisevqlvesggglvqpggslrlscaasgfnikdtyihwvrqapgkglewvariyptngy
tryadsvkgrftisadtskntaylqmnslraedtavyycsrwggdgfyamdywgqgtlvt
vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >3be1H (H:)
evqlvesggglvqpggslrlscaasgfnikdtyihwvrqapgkglewvariyptngytry
adsvkgrftisadtskntaylqmnslraedtavyycsrwggdgfyamdywgqgtlvtvss
astkgpsvfplapgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >3be1L (L:)
diqmtqspsslsasvgdrvtitcrasqdiprsisgyvawyqqkpgkapklliywgsylys
gvpsrfsgsgsgtdftltisslqpedfatyycqqhyttpptfgqgtkveikrtvaapsvf
ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
stltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >3be1L (L:)
diqmtqspsslsasvgdrvtitcrasqdiprsisgyvawyqqkpgkapklliywgsylys
gvpsrfsgsgsgtdftltisslqpedfatyycqqhyttpptfgqgtkveikrtvaapsvf
ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
stltlskadyekhkvyacevthqglsspvtksfnrg